Lucia De Franceschi

LDF_Picture,  April 13, 2018
Position
Associate Professor
Sections
Internal Medicine Section B
Academic sector
MED/09 - INTERNAL MEDICINE
Research sector (ERC)
LS3_7 - Cell signalling and cellular interactions

Telephone
0458124918
Fax
0458027473
E-mail
lucia|defranceschi*univr|it <== Replace | with . and * with @ to have the right email address.

Office Hours

Thursday, Hours 12:15 PM - 1:30 PM,   Policlinico G.B. Rossi lotto I, Floor 5° piano, room 

Curriculum

My scientific activity has focused on red cell pathologies, normal and pathologic erythropoiesis, hemoglobinopathies such as β-thalassemic syndromes and sickle cell disease (SCD) and hereditary rare anemias (i.e.: stomatocytosis, CDAII). An additional area of investigation is chorea-acanthocytosis and McLeod syndrome, which are neurodegenerative disorders involving also the erythroid compartment (Blood 118: 5652-63, 2011; Blood 128: 2976, 2016; J Neurosci 36: 12027, 2016). Through highly productive collaborations and keywork in my laboratory, my research has resulted in a number of breakthrough technologies and discoveries.  
 

Modules

Modules running in the period selected: 126.
Click on the module to see the timetable and course details.

Course Name Total credits Online Teacher credits Modules offered by this teacher
Combined Bachelor's + Master's degree in Medicine and Surgery Clinical Methodology (2018/2019)   10    DIDATTICA PRATICA DI SEMEIOTICA MEDICA [Gruppo Prof.ssa De Franceschi]
Combined Bachelor's + Master's degree in Medicine and Surgery Medical and antropological emergencies in third world countries (2018/2019)   1  eLearning 0.5 
Combined Bachelor's + Master's degree in Medicine and Surgery Medical clinic, gerontology and medical treatment (2018/2019)   24  eLearning 18  DIDATTICA PRATICA DI MEDICINA INTERNA [Gruppo Prof.ssa De Franceschi]
Combined Bachelor's + Master's degree in Dentistry and Dental Prosthetics Medical sciences 1st (2018/2019)   14  eLearning MEDICINA INTERNA
ATTIVITA' PRATICA IN MEDICINA INTERNA
Combined Bachelor's + Master's degree in Medicine and Surgery Clinical Methodology (2017/2018)   10    DIDATTICA PRATICA DI SEMEIOTICA MEDICA [Gruppo Prof.ssa De Franceschi]
Postgraduate Specialisation in Urology Internal Medicine (2017/2018)   2     
Postgraduate Specialisation in Internal Medicine Main clinical presentation related to major clinical feature in emergency medicine (2017/2018)   42    DIDATTICA FRONTALE
Combined Bachelor's + Master's degree in Medicine and Surgery Medical and antropological emergencies in third world countries (2017/2018)   1    0.5 
Combined Bachelor's + Master's degree in Medicine and Surgery Medical clinic, gerontology and medical treatment (2017/2018)   24    18  DIDATTICA PRATICA DI MEDICINA INTERNA [Gruppo Prof.ssa De Franceschi]
Combined Bachelor's + Master's degree in Dentistry and Dental Prosthetics Medical sciences 1st (2017/2018)   14  eLearning MEDICINA INTERNA
ATTIVITA' PRATICA IN MEDICINA INTERNA
Postgraduate Specialisation in Emergency and Urgent Medicine Medicina interna 2 (2017/2018)   58    0.34  DIDATTICA FRONTALE
Postgraduate Specialisation in Internal Medicine Medicina interna 2 (2017/2018)   57    0.83  DIDATTICA FRONTALE
Postgraduate Specialisation in Internal Medicine Medicina interna 3 (2017/2018)   57    0.83  DIDATTICA FRONTALE
Postgraduate Specialisation in Internal Medicine Medicina interna 4 (2017/2018)   57    0.83  DIDATTICA FRONTALE
Postgraduate Specialisation in Internal Medicine Medicina interna 5 (2017/2018)   42    0.5  DIDATTICA FRONTALE
Combined Bachelor's + Master's degree in Medicine and Surgery Clinical Methodology and Laboratory Medicine (2016/2017)   14  eLearning DIDATTICA PRATICA DI SEMEIOTICA, DI MEDICINA DI LABORATORIO [Gruppo Prof.ssa De Franceschi]
Postgraduate Specialisation in Internal Medicine Main clinical presentation related to major clinical feature in emergency medicine (2016/2017)   42    1.33  DIDATTICA FRONTALE
Combined Bachelor's + Master's degree in Medicine and Surgery Medical and antropological emergencies in third world countries (2016/2017)   1    0.5 
Combined Bachelor's + Master's degree in Medicine and Surgery Medical clinic, gerontology and medical treatment (2016/2017)   24  eLearning 18  DIDATTICA PRATICA DI MEDICINA INTERNA [Gruppo Prof.ssa De Franceschi]
Combined Bachelor's + Master's degree in Dentistry and Dental Prosthetics Medical sciences 1st (2016/2017)   14    MEDICINA INTERNA
ATTIVITA' PRATICA IN MEDICINA INTERNA
Postgraduate Specialisation in Emergency and Urgent Medicine Medicina interna 2 (2016/2017)   58    0.34  DIDATTICA FRONTALE
Postgraduate Specialisation in Internal Medicine Medicina interna 2 (2016/2017)   57    0.84  DIDATTICA FRONTALE
Postgraduate Specialisation in Internal Medicine Medicina interna 3 (2016/2017)   57    0.75  DIDATTICA FRONTALE
Postgraduate Specialisation in Internal Medicine Medicina interna 4 (2016/2017)   57    0.75  DIDATTICA FRONTALE
Postgraduate Specialisation in Gastroenterology Medicina interna 4 (2016/2017)   1    0.25 
Postgraduate Specialisation in Geriatrics Medicina interna 4 (2016/2017)   1    0.25 
Postgraduate Specialisation in Cardiovascular Diseases Medicina interna 4 (2016/2017)   1    0.38 
Postgraduate Specialisation in Infectious Diseases Medicina interna 4 (2016/2017)   1    0.25 
Postgraduate Specialisation in Medical Oncology Medicina interna 4 (2016/2017)   1    0.5 
Postgraduate Specialisation in Internal Medicine Medicina interna 5 (2016/2017)   42    0.5  DIDATTICA FRONTALE
Combined Bachelor's + Master's degree in Medicine and Surgery Clinical Methodology and Laboratory Medicine (2015/2016)   14  eLearning DIDATTICA PRATICA DI SEMEIOTICA, DI MEDICINA DI LABORATORIO [Gruppo Prof.ssa De Franceschi] (Didattica pratica di Semeiotica)
Combined Bachelor's + Master's degree in Medicine and Surgery Internal Medicine (2015/2016)   10    MEDICINA INTERNA
Postgraduate Specialisation in Internal Medicine Main clinical presentation related to major clinical feature in emergency medicine (2015/2016)   42    DIDATTICA FRONTALE
Combined Bachelor's + Master's degree in Medicine and Surgery Medical and antropological emergencies in third world countries (2015/2016)   1    0.5 
Combined Bachelor's + Master's degree in Medicine and Surgery Medical clinic, gerontology and medical treatment (2015/2016)   24    18  DIDATTICA PRATICA DI MEDICINA INTERNA [Gruppo Prof.ssa De Franceschi]
Combined Bachelor's + Master's degree in Dentistry and Dental Prosthetics Medical sciences 1st (2015/2016)   14    MEDICINA INTERNA
ATTIVITA' PRATICA IN MEDICINA INTERNA
Postgraduate Specialisation in Emergency and Urgent Medicine Medicina interna 2 (2015/2016)   58    0.34  DIDATTICA FRONTALE
Postgraduate Specialisation in Internal Medicine Medicina interna 2 (2015/2016)   57    0.5  DIDATTICA FRONTALE
Postgraduate Specialisation in Internal Medicine Medicina interna 3 (2015/2016)   57    0.5  DIDATTICA FRONTALE
Postgraduate Specialisation in Cardiovascular Diseases Medicina interna 4 (2015/2016)   1    0.38 
Postgraduate Specialisation in Internal Medicine Medicina interna 4 (2015/2016)   57    0.5  DIDATTICA FRONTALE
Postgraduate Specialisation in Medical Oncology Medicina interna 4 (2015/2016)   1    0.5 
Postgraduate Specialisation in Rheumatology Medicina interna 4 (2015/2016)   1    0.25 
Postgraduate Specialisation in Internal Medicine Medicina interna 5 (2015/2016)   42    0.4  DIDATTICA FRONTALE
Combined Bachelor's + Master's degree in Medicine and Surgery Clinical Methodology and Laboratory Medicine (2014/2015)   14  eLearning DIDATTICA PRATICA DI SEMEIOTICA, DI MEDICINA DI LABORATORIO [Gruppo Prof.ssa De Franceschi] (Didattica pratica di Semeiotica)
Combined Bachelor's + Master's degree in Medicine and Surgery Internal Medicine (2014/2015)   10    MEDICINA INTERNA
Postgraduate Specialisation in Internal Medicine Main clinical presentation related to major clinical feature in emergency medicine (2014/2015)   42    DIDATTICA FRONTALE
Combined Bachelor's + Master's degree in Medicine and Surgery Medical and antropological emergencies in third world countries (2014/2015)   1    0.25 
Combined Bachelor's + Master's degree in Medicine and Surgery Medical clinic, gerontology and medical treatment (2014/2015)   24    18  DIDATTICA PRATICA DI MEDICINA INTERNA [Gruppo Prof.ssa De Franceschi]
Combined Bachelor's + Master's degree in Dentistry and Dental Prosthetics Medical sciences 1st (2014/2015)   14    MEDICINA INTERNA
ATTIVITA' PRATICA IN MEDICINA INTERNA
Postgraduate Specialisation in Internal Medicine Medicina interna 2 (2014/2015)   57    0.5  DIDATTICA FRONTALE
Postgraduate Specialisation in Internal Medicine Medicina interna 3 (2014/2015)   57    0.5  DIDATTICA FRONTALE
Postgraduate Specialisation in Rheumatology Medicina interna 4 (2014/2015)   1    0.25 
Postgraduate Specialisation in Internal Medicine Medicina interna 4 (2014/2015)   57    0.5  DIDATTICA FRONTALE
Postgraduate Specialisation in Internal Medicine Medicina interna 5 (discipline specifiche della tipologia) (2014/2015)   38    1.76  DIDATTICA FRONTALE
Combined Bachelor's + Master's degree in Medicine and Surgery Clinical Methodology and Laboratory Medicine (2013/2014)   14    METODOLOGIA CLINICA, SEMEIOTICA MEDICA E CHIRURGICA
DIDATTICA PRATICA DI SEMEIOTICA, DI MEDICINA DI LABORATORIO [Gruppo Prof. ssa De Franceschi] (Didattica pratica di Semeiotica)
Combined Bachelor's + Master's degree in Medicine and Surgery Internal Medicine (2013/2014)   10    MEDICINA INTERNA
Combined Bachelor's + Master's degree in Medicine and Surgery Medical and antropological emergencies in third world countries (2013/2014)   1    0.5 
Specialist degree in Medicine and Surgery (single cycle) Medical clinic, gerontology and medical treatment (2013/2014)   23    15  INTERNATO DI MEDICINA INTERNA [Gruppo Prof.ssa De Franceschi]
Postgraduate Specialisation in Orthopaedics and Traumatology Medicina interna 1 (tronco comune - clinico) (2013/2014)   1    0.5 
Postgraduate Specialisation in Internal Medicine Medicina interna 4 (2013/2014)   1    0.25 
Postgraduate Specialisation in Nephrology Medicina interna 4 (2013/2014)   1    0.25 
Postgraduate Specialisation in Internal Medicine Medicina interna 5 (discipline specifiche della tipologia) (2013/2014)   41    0.88  DIDATTICA FRONTALE
Postgraduate Specialisation in Orthopaedics and Traumatology Medicina interna (tronco comune - emergenza e pronto soccorso) (2013/2014)   1    0.5 
Specialist degree in Medicine and Surgery (single cycle) Biomedicine in clinics, a ticket of return: the frontiers of post-translational medicine (2012/2013)   1    0.5 
Combined Bachelor's + Master's degree in Medicine and Surgery Clinical Methodology and Laboratory Medicine (2012/2013)   14    METODOLOGIA CLINICA, SEMEIOTICA MEDICA E CHIRURGICA
DIDATTICA PRATICA DI SEMEIOTICA, DI MEDICINA DI LABORATORIO [Gruppo Prof. De Franceschi] (Didattica pratica di Semeiotica)
Specialist degree in Medicine and Surgery (single cycle) Internal Medicine (2012/2013)   11    MEDICINA INTERNA: LEZIONI
Specialist degree in Medicine and Surgery (single cycle) Medical and antropological emergencies in third world countries (2012/2013)   1    0.5 
Specialist degree in Medicine and Surgery (single cycle) Medical clinic, gerontology and medical treatment (2012/2013)   23    15  INTERNATO DI MEDICINA INTERNA [Gruppo Prof.ssa De Franceschi]
Postgraduate Specialisation in Orthopaedics and Traumatology Medicina interna 1 (tronco comune - clinico) (2012/2013)   1    0.5 
Postgraduate Specialisation in Internal Medicine Medicina interna 4 (2012/2013)   1    0.25 
Postgraduate Specialisation in Nephrology Medicina interna 4 (2012/2013)   1    0.25 
Postgraduate Specialisation in Internal Medicine Medicina interna 5 (discipline specifiche della tipologia) (2012/2013)   43    0.87  DIDATTICA FRONTALE
Postgraduate Specialisation in Orthopaedics and Traumatology Medicina interna (tronco comune - emergenza e pronto soccorso) (2012/2013)   1    0.5 
Specialist degree in Medicine and Surgery (single cycle) Biomedicine in clinics, a ticket of return: the frontiers of post-translational medicine (2011/2012)   1    0.5 
Specialist degree in Medicine and Surgery (single cycle) Clinical Methodology and Laboratory Medicine (2011/2012)   17    SEMEIOTICA MEDICA E METODOLOGIA CLINICA: LEZIONI
INTERNATO DI SEMEIOTICA MEDICA [Gruppo Prof. De Franceschi]
Specialist degree in Medicine and Surgery (single cycle) Internal Medicine (2011/2012)   11    MEDICINA INTERNA: LEZIONI
Specialist degree in Medicine and Surgery (single cycle) Medical and antropological emergencies in third world countries (2011/2012)   1    0.4 
Specialist degree in Medicine and Surgery (single cycle) Medical clinic, gerontology and medical treatment (2011/2012)   23    15  INTERNATO DI MEDICINA INTERNA [Gruppo Prof.ssa De Franceschi]
Postgraduate Specialisation in Orthopaedics and Traumatology Medicina Interna (1°anno - TRONCO COMUNE - CLINICO - Didattica Frontale) (2011/2012)   1    0.5 
Postgraduate Specialisation in Internal Medicine Medicina interna (4°anno - TRONCO COMUNE - Didattica frontale) (2011/2012)   1    0.25 
Postgraduate Specialisation in Cardiovascular Diseases Medicina interna (4°anno - TRONCO COMUNE - Didattica frontale) (2011/2012)   1    0.25 
Postgraduate Specialisation in Orthopaedics and Traumatology Medicina interna (TRONCO COMUNE - Emergenza e P.S.) (2011/2012)   1    0.5 
School of Specialisation in Internal Medicine Metodologia clinica (V anno) (2011/2012)   74    37 
Specialist degree in Medicine and Surgery (single cycle) Biomedicine in clinics, a ticket of return: the frontiers of post-translational medicine (2010/2011)   1    0.5 
Specialist degree in Medicine and Surgery (single cycle) Clinical Methodology and Laboratory Medicine (2010/2011)   17    0.5  SEMEIOTICA MEDICA E METODOLOGIA CLINICA: LEZIONI
INTERNATO DI SEMEIOTICA MEDICA [Prof.ssa De Franceschi]
Specialist degree in Medicine and Surgery (single cycle) Internal Medicine (2010/2011)   11    MEDICINA INTERNA: LEZIONI
Specialist degree in Medicine and Surgery (single cycle) Medical and antropological emergencies in third world countries (2010/2011)   1    0.34 
Specialist degree in Medicine and Surgery (single cycle) Medical clinic, gerontology and medical treatment (2010/2011)   23    15  INTERNATO DI MEDICINA INTERNA [Gruppo Prof.ssa De Franceschi]
Postgraduate Specialisation in Emergency and Urgent Medicine Medicina Interna (1° anno - DISCIPLINE SPECIFICHE DELLA TIPOLOGIA - Didattica Frontale) (2010/2011)   2    0.37 
Postgraduate Specialisation in Orthopaedics and Traumatology Medicina Interna (TRONCO COMUNE - Clinico - Didattica Frontale) (2010/2011)   1    0.5 
Postgraduate Specialisation in Orthopaedics and Traumatology Medicina interna (TRONCO COMUNE - Emergenza e P.S.) (2010/2011)   1    0.5 
Specialist degree in Medicine and Surgery (single cycle) Clinical Methodology and Laboratory Medicine (2009/2010)   17    INTERNATO DI SEMEIOTICA MEDICA [Gruppo Prof.ssa De Franceschi]
Specialist degree in Medicine and Surgery (single cycle) Internal Medicine (2009/2010)   11    MEDICINA INTERNA: LEZIONI
Specialist degree in Medicine and Surgery (single cycle) Medical and antropological emergencies in third world countries (2009/2010)   1    0.3 
Specialist degree in Medicine and Surgery (single cycle) Medical clinic, gerontology and medical treatment (2009/2010)   23    15  INTERNATO DI MEDICINA INTERNA [Gruppo Prof.ssa De Franceschi]
Specialist degree in Medicine and Surgery (single cycle) Post-translational clinical medicine (2009/2010)   1    0.5 
Postgraduate Specialisation in Internal Medicine MEDICINA INTERNA (2°anno - DISCIPLINE SPECIFICHE DELLA TIPOLOGIA - Did. Frontale) (2009/2010)   9    0.37 
Postgraduate Specialisation in Orthopaedics and Traumatology Medicina Interna (TRONCO COMUNE - Clinico - Didattica Frontale) (2009/2010)   1    0.5 
Postgraduate Specialisation in Orthopaedics and Traumatology Medicina interna (TRONCO COMUNE - Emergenza e P.S.) (2009/2010)   1    0.5 
Specialist degree in Medicine and Surgery (single cycle) Clinical and molecular medicine in post-genomic era (2008/2009)   1   
Specialist degree in Medicine and Surgery (single cycle) Clinical Methodology and Laboratory Medicine (2008/2009)   17    Internato di Semeiotica medica
Specialist degree in Medicine and Surgery (single cycle) Internal Medicine (2008/2009)   11    0.25  Medicina interna: lezioni
Specialist degree in Medicine and Surgery (single cycle) Medical and antropological emergencies in third world countries (2008/2009)   1   
Specialist degree in Medicine and Surgery (single cycle) Medical clinic, gerontology and medical treatment (2008/2009)   23    15  Internato di Medicina Interna [Gruppo De Franceschi]
Postgraduate Specialisation in Orthopaedics and Traumatology Medicina Interna (TRONCO COMUNE - Clinico - Didattica Frontale) (2008/2009)   1    0.5 
Postgraduate Specialisation in Orthopaedics and Traumatology Medicina interna (TRONCO COMUNE - Emergenza e P.S.) (2008/2009)   1    0.5 
School of Specialisation in Rheumatology Proteomica clinica (2008/2009)   10    10 
Specialist degree in Medicine and Surgery (single cycle) Clinical Methodology and Laboratory Medicine (2007/2008)   17    Internato di Semeiotica medica
Specialist degree in Medicine and Surgery (single cycle) Internal Medicine (2007/2008)   11    0.5  Medicina interna: lezioni
Specialist degree in Medicine and Surgery (single cycle) Medical clinic, gerontology and medical treatment (2007/2008)   23    15  Internato di Medicina Interna
Specialist degree in Medicine and Surgery (single cycle) Clinical Methodology and Laboratory Medicine (2006/2007)   17    Internato di Semeiotica medica
Specialist degree in Medicine and Surgery (single cycle) Internal Medicine (2006/2007)   11    0.4  Medicina interna: lezioni
Specialist degree in Medicine and Surgery (single cycle) Medical clinic, gerontology and medical treatment (2006/2007)   23    15  Internato di Medicina Interna
Specialist degree in Medicine and Surgery (single cycle) Clinical Methodology and Laboratory Medicine (2005/2006)   17    Internato di Semeiotica medica
Specialist degree in Medicine and Surgery (single cycle) Internal Medicine (2005/2006)   11    0.4  Medicina interna: lezioni
Specialist degree in Medicine and Surgery (single cycle) Medical clinic, gerontology and medical treatment (2005/2006)   23    15  Internato di Medicina Interna

 
Skills
Topic Description Research area
red cell disorders and pathologic erythropoiesis My scientific activity has focused on red cell pathologies, normal and pathologic erythropoiesis, hemoglobinopathies such as β-thalassemic syndromes and sickle cell disease (SCD) and hereditary rare anemias (i.e.: stomatocytosis, CDAII). An additional area of investigation is chorea-acanthocytosis and McLeod syndrome, which are neurodegenerative disorders involving also the erythroid compartment (Blood 118: 5652-63, 2011; Blood 128: 2976, 2016; J Neurosci 36: 12027, 2016). Through highly productive collaborations and keywork in my laboratory, my research has resulted in a number of breakthrough technologies and discoveries. Hematology
Projects
Title Starting date
Analisi proteomica dell'eritropoiesis talassemica e di modelli correlati allo stimolo ipossico 3/22/10
ENERCA: european network for rare anemias 3 1/6/09
EURONA: European Network on Neuroacanthocytosis: A timely approach to decode links between blood and brain, comprehend neurodegeneration and ease patient suffering 3/12/08
Analysis of functional and post-traslational modifications in abnormal red cells from neuroacanthocytosis’ 1/1/07
ANALISI PROTEOMICA DEI PROGENITORI ERITROIDI IN ANEMIE ASSOCIATE A SOVRACCARICO MARZIALE (2006) 1/1/06
Caratterizzazione molecolare dell’eritropoiesi: analisi post-genomica e funzionale del profilo di espressione proteica 11/30/04
Caratterizzazione molecolare dell'eritropoiesi:analisi post-genomica e funzionale del progiloi di espressione proteica 9/30/04
Approccio proteomico funzionale ai sistemi di trasporto ionico di membrana coinvolti nella regolazione del volume cellulare e nella crescita nei precursori eritroidi: ruolo del cotrsporto K-Cl nei globuli rossi normali e beta talassemici. (2004) 1/1/04
Erythroid proteomics: clinical and therapeutic implications 1/10/03
Approccio proteomico al danno ossidativo della membrana eritrocitaria nella beta talassemia e drepanocitosi 12/16/02
Magnesium and sickle cell disease 12/1/02
Magnesium and Sickle Cell Disease 9/1/02
Studio dei determinanti genetici ed acquisti dell'ipertensione arteriosa e della progressione arteriosclerotica ad essa correlata 7/1/02
Molecular mechanisms of cell dehydration in sickle cell disease and beta thalassemia. Regulation ofK-Cl cotransport in normal and diseased erythrocytes. 7/1/99
Caratterizzazione dei sistemi di trasporto coinvolti nella regolazione del volume cellulare in patologie congenite del globulo rosso. (1999) 1/1/99
Novel Gardos channel blockers and sickled red blood cell dehydration. 11/1/98




Organisation

Department facilities