Endothelial progenitor cells in endogenous cellular repair during the development of atherosclerotic cardiovascular disease: role of cyclo-oxygenases.

Starting date
July 1, 2011
Duration (months)
36
Departments
Medicine
Managers or local contacts
Delva Pietro , Fava Cristiano , Minuz Pietro
Keyword
cyclooxygenase, endothelial progenitor cell, myocardialo infarction

The aim of this project will be to clarify the role of cyclooxygenase (COX) pathway in endothelial progenitor cell (EPC) function and in particular the contribution of prostacyclin in homing, survival and proliferation of EPC. These results will be useful to the development of novel strategies of cell-based therapy of myocardial infarction.

Project participants

Pietro Minuz
Full Professor

Activities

Research facilities