Pubblicazioni

Autori:

Knight, Stephen R; Shaw, Catherine A; Pius, Riinu; Drake, Thomas M; Norman, Lisa; Ademuyiwa, Adesoji O; Adisa, Adewale O; Aguilera, Maria Lorena; Al-Saqqa, Sara W; Al-Slaibi, Ibrahim; Bhangu, Aneel; Biccard, Bruce M; Brocklehurst, Peter; Costas-Chavarri, Ainhoa; Chu, Kathryn; Dare, Anna; Elhadi, Muhammed; Fairfield, Cameron J; Fitzgerald, J Edward; Ghosh, Dhruv; Glasbey, James; van Berge Henegouwen, Mark I.; Ingabire, J. C. Allen; Kingham, T Peter; Lapitan, Marie Carmela; Lawani, Ismaïl; Lieske, Bettina; Lilford, Richard; Martin, Janet; Mclean, Kenneth A; Moore, Rachel; Morton, Dion; Nepogodiev, Dmitri; Ntirenganya, Faustin; Pata, Francesco; Pinkney, Thomas; Qureshi, Ahmad Uzair; Ramos-De la Medina, Antonio; Riad, Aya; Salem, Hosni Khairy; Simões, Joana; Spence, Richard; Smart, Neil; Tabiri, Stephen; Thomas, Hannah; Weiser, Thomas G; West, Malcolm; Whitaker, John; Harrison, Ewen M; Gjata, Arben; Modolo, Maria Marta; King, Sebastian; Chan, Erick; Nahar, Sayeda Nazmun; Waterman, Ade; Vervoort, Dominique; Lawani, Ismaïl; Bedada, Alemayehu Ginbo; De Azevedo, Bernardo; Figueiredo, Ana Gabriela; Sokolov, Manol; Barendegere, Venerand; Ekwen, Gerald; Agarwal, Arnav; Dare, Anna; Liu, Qinyang; Camilo Correa, Juan; Malemo, Kalisya Luc; Bake, Jacques; Mihanovic, Jakov; Kunčarová, Kamila; Orhalmi, Julius; Salem, Hosni; Teras, Jyri; Kechagias, Aristotelis; Arnaud, Alexis P; Lindert, Judith; Tabiri, Stephen; Kalles, Vasileios; Aguilera-Arevalo, Maria-Lorena; Recinos, Gustavo; Baranyai, Zsolt; Kumar, Basant; Neelamraju Lakshmi, Harish; Zachariah, Sanoop Koshy; Alexander, Philip; Kumar Venkatappa, Sunil; Pramesh, C; Amandito, Radhian; Fleming, Christina; Ansaloni, Luca; Pata, Francesco; Pellino, Gianluca; Altibi, Ahmed M.; Nour, Ibrahim; Hamdun, Intisar; Elhadi, Muhammed; Ghellai, Ali M.; Venskutonis, Donatas; Poskus, Tomas; Zilinskas, Justas; Whitaker, John; Malemia, Precious; Tew, Yong Yong; Borg, Elaine; Ellul, Sarah; Ramos-De la Medina, Antonio; Wafqui, fatima Zahraa; Borowski, David W; van Dalen, Anne Sophie; Wells, Cameron; Adamou, Harissou; Ademuyiwa, Adesoji; Adisa, Adewale; Søreide, Kjetil; Qureshi, Ahmad Uzair; Al-Slaibi, Ibrahim; Al Saqqa, Sara; Alser, Osaid; Tahboub, Haya; Segovia Lohse, Helmut Alfredo; Shu Yip, Sebastian; Lapitan, Marie Carmela; Major, Piotr; Simões, Joana; Sampaio Soares, António; Bratu, Matei Razvan; Litvin, Andrey; Vardanyan, Armen; Allen Ingabire, Jc; Costas-Chavarri, Ainhoa; Gudal, Ahmad; Albati, Naif; Juloski, Jovan; Lieske, Bettina; Rems, Miran; Rayne, Sarah; Van Straten, Stephanie; Moodley, Yoshan; Chu, Kathryn; Moore, Rachel; Ortega Vázquez, Irene; Ruiz-Tovar, Jaime; Senanayake, Kithsiri Janakantha; Thalgaspitiya, Sujeewa Priyantha Bandara; Omer, Omer Abdelbagi; Homeida, Anmar; Cengiz, Yucel; Clerc, Daniel; Alshaar, Muhammad; Bouaziz, Hanen; Altinel, Yuksel; Doe, Matthew; Freigofer, Maryna; Teasdale, Ella; Kabariti, Rakan; Clements, Joshua Michael; Knight, Stephen Richard; Ashfaq, Ahsan; Azodo, Ijeoma; Wagner, Gabriela; Trostchansky, Ivan; Maimbo, Mayaba; Linyama, David; Nina, Helidon; Zeko, Amanda; Fermani, Claudio Gabriel; Modolo, Maria Marta; Villalobos, Santiago; Carballo, Federico; Farina, Pablo; Guckenheimer, Sebastian; Dickfos, Marilla; Ajmera, Ankit; Chong, Chester; Gourlay, Ralph; Hussaini, Sikandar; Lee, Yi Jia; Majid, Adeeb; Martin, Peter; Miles, Rebecca; Morris, Owen James; Phua, Jamie; Ridley, William; Saluja, Tarunpreet; Tan, Ryan Renxin; Teh, Jen; Wells, Anna; Arora, Bharti; Dollie, Qaasim; Ho, Debbie; Ma, Yanru; Perera, Omattage Mahasha; Truong, Anthony; Dawson, Amanda Caroline; Lim, Bryan; Pahalawatta, Upuli; Phan, Jacqueline; Woon-Shoo-Tong, Xiao-Ming Sarah; Yeoh, Andrea; Charman, Lillian; Drane, Andrew; Laura, Sharon; Lo, Charmaine Chu Wen; Mozes, Amy; Poon, Rita; Tan, Hao Han; Wall, Ellen; Chopra, Prakshi; De Giovanni, Jasmine; Dhital, Bal; Draganic, Brian; Duller, Alexander; Gani, Jonathan; Goh, Yao Kuan; Jeong, Jun Young; Mcmanus, Bre

Titolo:

Effects of hospital facilities on patient outcomes after cancer surgery: an international, prospective, observational study

Anno:

2022

Tipologia prodotto:

Articolo in Rivista

Tipologia ANVUR:

Articolo su rivista

Lingua:

Inglese

Referee:

No

Nome rivista:

THE LANCET GLOBAL HEALTH

ISSN Rivista:

2214-109X

N° Volume:

10

Numero o Fascicolo:

7

Intervallo pagine:

e1003-e1011

Parole chiave:

Humans; Income; Postoperative Period; Poverty; Prospective Studies; Hospitals; Neoplasms

Breve descrizione dei contenuti:

Background Early death after cancer surgery is higher in low-income and middle-income countries (LMICs) compared with in high-income countries, yet the impact of facility characteristics on early postoperative outcomes is unknown. The aim of this study was to examine the association between hospital infrastructure, resource availability, and processes on early outcomes after cancer surgery worldwide.Methods A multimethods analysis was performed as part of the GlobalSurg 3 study-a multicentre, international, prospective cohort study of patients who had surgery for breast, colorectal, or gastric cancer. The primary outcomes were 30-day mortality and 30-day major complication rates. Potentially beneficial hospital facilities were identified by variable selection to select those associated with 30-day mortality. Adjusted outcomes were determined using generalised estimating equations to account for patient characteristics and country-income group, with population stratification by hospital.Findings Between April 1, 2018, and April 23, 2019, facility-level data were collected for 9685 patients across 238 hospitals in 66 countries (91 hospitals in 20 high-income countries; 57 hospitals in 19 upper-middle-income countries; and 90 hospitals in 27 low-income to lower-middle-income countries). The availability of five hospital facilities was inversely associated with mortality: ultrasound, CT scanner, critical care unit, opioid analgesia, and oncologist. After adjustment for case-mix and country income group, hospitals with three or fewer of these facilities (62 hospitals, 1294 patients) had higher mortality compared with those with four or five (adjusted odds ratio [OR] 3.85 [95% CI 2.58-5.75]; p<0.0001), with excess mortality predominantly explained by a limited capacity to rescue following the development of major complications (63.0% vs 82.7%; OR 0.35 [0.23-0.53]; p<0.0001). Across LMICs, improvements in hospital facilities would prevent one to three deaths for every 100 patients undergoing surgery for cancer.Interpretation Hospitals with higher levels of infrastructure and resources have better outcomes after cancer surgery, independent of country income. Without urgent strengthening of hospital infrastructure and resources, the reductions in cancer-associated mortality associated with improved access will not be realised. Copyright (C) 2022 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license.

Id prodotto:

130573

Handle IRIS:

11562/1078666

ultima modifica:

23 febbraio 2023

Citazione bibliografica:

Knight, Stephen R; Shaw, Catherine A; Pius, Riinu; Drake, Thomas M; Norman, Lisa; Ademuyiwa, Adesoji O; Adisa, Adewale O; Aguilera, Maria Lorena; Al-Saqqa, Sara W; Al-Slaibi, Ibrahim; Bhangu, Aneel; Biccard, Bruce M; Brocklehurst, Peter; Costas-Chavarri, Ainhoa; Chu, Kathryn; Dare, Anna; Elhadi, Muhammed; Fairfield, Cameron J; Fitzgerald, J Edward; Ghosh, Dhruv; Glasbey, James; van Berge Henegouwen, Mark I.; Ingabire, J. C. Allen; Kingham, T Peter; Lapitan, Marie Carmela; Lawani, Ismaïl; Lieske, Bettina; Lilford, Richard; Martin, Janet; Mclean, Kenneth A; Moore, Rachel; Morton, Dion; Nepogodiev, Dmitri; Ntirenganya, Faustin; Pata, Francesco; Pinkney, Thomas; Qureshi, Ahmad Uzair; Ramos-De la Medina, Antonio; Riad, Aya; Salem, Hosni Khairy; Simões, Joana; Spence, Richard; Smart, Neil; Tabiri, Stephen; Thomas, Hannah; Weiser, Thomas G; West, Malcolm; Whitaker, John; Harrison, Ewen M; Gjata, Arben; Modolo, Maria Marta; King, Sebastian; Chan, Erick; Nahar, Sayeda Nazmun; Waterman, Ade; Vervoort, Dominique; Lawani, Ismaïl; Bedada, Alemayehu Ginbo; De Azevedo, Bernardo; Figueiredo, Ana Gabriela; Sokolov, Manol; Barendegere, Venerand; Ekwen, Gerald; Agarwal, Arnav; Dare, Anna; Liu, Qinyang; Camilo Correa, Juan; Malemo, Kalisya Luc; Bake, Jacques; Mihanovic, Jakov; Kunčarová, Kamila; Orhalmi, Julius; Salem, Hosni; Teras, Jyri; Kechagias, Aristotelis; Arnaud, Alexis P; Lindert, Judith; Tabiri, Stephen; Kalles, Vasileios; Aguilera-Arevalo, Maria-Lorena; Recinos, Gustavo; Baranyai, Zsolt; Kumar, Basant; Neelamraju Lakshmi, Harish; Zachariah, Sanoop Koshy; Alexander, Philip; Kumar Venkatappa, Sunil; Pramesh, C; Amandito, Radhian; Fleming, Christina; Ansaloni, Luca; Pata, Francesco; Pellino, Gianluca; Altibi, Ahmed M.; Nour, Ibrahim; Hamdun, Intisar; Elhadi, Muhammed; Ghellai, Ali M.; Venskutonis, Donatas; Poskus, Tomas; Zilinskas, Justas; Whitaker, John; Malemia, Precious; Tew, Yong Yong; Borg, Elaine; Ellul, Sarah; Ramos-De la Medina, Antonio; Wafqui, fatima Zahraa; Borowski, David W; van Dalen, Anne Sophie; Wells, Cameron; Adamou, Harissou; Ademuyiwa, Adesoji; Adisa, Adewale; Søreide, Kjetil; Qureshi, Ahmad Uzair; Al-Slaibi, Ibrahim; Al Saqqa, Sara; Alser, Osaid; Tahboub, Haya; Segovia Lohse, Helmut Alfredo; Shu Yip, Sebastian; Lapitan, Marie Carmela; Major, Piotr; Simões, Joana; Sampaio Soares, António; Bratu, Matei Razvan; Litvin, Andrey; Vardanyan, Armen; Allen Ingabire, Jc; Costas-Chavarri, Ainhoa; Gudal, Ahmad; Albati, Naif; Juloski, Jovan; Lieske, Bettina; Rems, Miran; Rayne, Sarah; Van Straten, Stephanie; Moodley, Yoshan; Chu, Kathryn; Moore, Rachel; Ortega Vázquez, Irene; Ruiz-Tovar, Jaime; Senanayake, Kithsiri Janakantha; Thalgaspitiya, Sujeewa Priyantha Bandara; Omer, Omer Abdelbagi; Homeida, Anmar; Cengiz, Yucel; Clerc, Daniel; Alshaar, Muhammad; Bouaziz, Hanen; Altinel, Yuksel; Doe, Matthew; Freigofer, Maryna; Teasdale, Ella; Kabariti, Rakan; Clements, Joshua Michael; Knight, Stephen Richard; Ashfaq, Ahsan; Azodo, Ijeoma; Wagner, Gabriela; Trostchansky, Ivan; Maimbo, Mayaba; Linyama, David; Nina, Helidon; Zeko, Amanda; Fermani, Claudio Gabriel; Modolo, Maria Marta; Villalobos, Santiago; Carballo, Federico; Farina, Pablo; Guckenheimer, Sebastian; Dickfos, Marilla; Ajmera, Ankit; Chong, Chester; Gourlay, Ralph; Hussaini, Sikandar; Lee, Yi Jia; Majid, Adeeb; Martin, Peter; Miles, Rebecca; Morris, Owen James; Phua, Jamie; Ridley, William; Saluja, Tarunpreet; Tan, Ryan Renxin; Teh, Jen; Wells, Anna; Arora, Bharti; Dollie, Qaasim; Ho, Debbie; Ma, Yanru; Perera, Omattage Mahasha; Truong, Anthony; Dawson, Amanda Caroline; Lim, Bryan; Pahalawatta, Upuli; Phan, Jacqueline; Woon-Shoo-Tong, Xiao-Ming Sarah; Yeoh, Andrea; Charman, Lillian; Drane, Andrew; Laura, Sharon; Lo, Charmaine Chu Wen; Mozes, Amy; Poon, Rita; Tan, Hao Han; Wall, Ellen; Chopra, Prakshi; De Giovanni, Jasmine; Dhital, Bal; Draganic, Brian; Duller, Alexander; Gani, Jonathan; Goh, Yao Kuan; Jeong, Jun Young; Mcmanus, Bre, Effects of hospital facilities on patient outcomes after cancer surgery: an international, prospective, observational study «THE LANCET GLOBAL HEALTH» , vol. 10 , n. 7 , 2022 , pp. e1003-e1011

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