Pubblicazioni

Autori:

Bezzerri, Valentino; Vella, Antonio; Gennaro, Gianfranco Di; Ortolani, Riccardo; Nicolis, Elena; Cesaro, Simone; Fabrizzi, Benedetta; Bronte, Vincenzo; Corey, Seth J; Cipolli, Marco

Titolo:

Peripheral blood immunophenotyping in a large cohort of patients with Shwachman-Diamond syndrome

Anno:

2019

Tipologia prodotto:

Articolo in Rivista

Tipologia ANVUR:

Articolo su rivista

Lingua:

Inglese

Referee:

No

Nome rivista:

PEDIATRIC BLOOD & CANCER

ISSN Rivista:

1545-5009

N° Volume:

66

Numero o Fascicolo:

5

Intervallo pagine:

27597-27601

Parole chiave:

Shwachman-Diamond syndrome; bone marrow failure; double-negative T cells; immunophenotype; neutropenia

Breve descrizione dei contenuti:

Shwachman-Diamond syndrome (SDS) is one of the more common inherited bone marrow failure syndromes, characterized by neutropenia, occasional thrombocytopenia, and anemia. Bone marrow evaluation reveals an increased number of monocytes and mature B cells along with decreased granulocytes. However, little is known about the subpopulations of peripheral blood cells, and few previous publications have been based on a small number of patients. Here, we report a comprehensive immunophenotypic analysis from a cohort of 37 SDS patients who display impairment mostly in the myeloid compartment with a deficiency also in the number of B cells and CD4/CD8 double-negative T cells.

Id prodotto:

109263

Handle IRIS:

11562/997268

ultima modifica:

15 novembre 2022

Citazione bibliografica:

Bezzerri, Valentino; Vella, Antonio; Gennaro, Gianfranco Di; Ortolani, Riccardo; Nicolis, Elena; Cesaro, Simone; Fabrizzi, Benedetta; Bronte, Vincenzo; Corey, Seth J; Cipolli, Marco, Peripheral blood immunophenotyping in a large cohort of patients with Shwachman-Diamond syndrome «PEDIATRIC BLOOD & CANCER» , vol. 66 , n. 5 , 2019 , pp. 27597-27601

Consulta la scheda completa presente nel repository istituzionale della Ricerca di Ateneo