Anti PSMA immunotoxins activity against prostate cancer cell lines.
Year:
2002
Type of item:
Abstract in rivista
Tipologia ANVUR:
Abstract su rivista
Language:
Inglese
Keyword:
ricin; immunotoxins; Prostate Specific Membrane Antigen (PSMA); prostate cancer
Short description of contents:
Immunotherapy with monoclonal antibody (mAb)-vehicled toxins may be a novel treatment option for the management of androgen-independent Prostate Cancer. To investigate the
therapeutic potential of anti-prostate specific membrane antigen (PSMA) mAb-ricin A-chain Immunotoxins (ITS) in monolayer and 3D cell cultures of prostate carcinoma cell lines (LNCaP), (J591, PEQ226.5, PM2PO79.1).