Experimental model in neurodegenerative diseases (2023/2024)

Course code
cod wi: DT000486
Name of lecturer
Elena Zenaro
Coordinator
Elena Zenaro
Number of ECTS credits allocated
1
Academic sector
MED/04 - EXPERIMENTAL MEDICINE AND PATHOPHYSIOLOGY
Language of instruction
Italian
Location
VERONA
Period
Anno accademico 2023/2024 Dottorato di Ricerca dal Oct 1, 2023 al Sep 30, 2024.

Lesson timetable

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Learning outcomes

Understand the concept of neurodegenerative disease, from the molecular and cellular mechanisms involved and the various forms of the disease. Understand that there are various disease models, from the simplest single-cell in-vitro, to the more complex 3D such as organoids, up to in-vivo models.

Syllabus

In the first parts of the lesson, students will be introduced to the concept of neurodegenerative disease, the molecular and cellular mechanisms involved and the various forms of disease. In the second part, an overview will be given of the various disease models, from the simplest unicellular in-vitro models, to the more complex 3D ones such as organoids, up to the in-vivo models. The study methods most used in the laboratory will also be discussed, such as microscopy, immunofluorescence techniques, transcriptome analysis and flow cytometric technologies. The various models will also be compared from a scientific, practical and economic point of view. Finally, some recently published articles will be taken into consideration with the aim of illustrating how these diseases can be studied in the laboratory.

Assessment methods and criteria

not expected

Studying

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