Lucia De Franceschi

Curriculum

•   Competenze Scientifiche_Ita   (docx, it, 16 KB, 14/04/18)
•   CV_English   (docx, en, 0 KB, 13/04/18)
•   CV_Italian_2021   (pdf, it, 116 KB, 14/09/21)
•   Scientific profile_Eng   (docx, en, 14 KB, 14/04/18)

My scientific activity has focused on red cell pathologies, normal and pathologic erythropoiesis, hemoglobinopathies such as β-thalassemic syndromes and sickle cell disease (SCD) and hereditary rare anemias (i.e.: stomatocytosis, CDAII). An additional area of investigation is chorea-acanthocytosis and McLeod syndrome, which are neurodegenerative disorders involving also the erythroid compartment (Blood 118: 5652-63, 2011; Blood 128: 2976, 2016; J Neurosci 36: 12027, 2016). Through highly productive collaborations and keywork in my laboratory, my research has resulted in a number of breakthrough technologies and discoveries.  
 

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Projects

Title	Starting date
Analisi proteomica dell'eritropoiesis talassemica e di modelli correlati allo stimolo ipossico	3/22/10
ENERCA: european network for rare anemias 3	1/6/09
EURONA: European Network on Neuroacanthocytosis: A timely approach to decode links between blood and brain, comprehend neurodegeneration and ease patient suffering	3/12/08
Analysis of functional and post-traslational modifications in abnormal red cells from neuroacanthocytosis’	1/1/07
ANALISI PROTEOMICA DEI PROGENITORI ERITROIDI IN ANEMIE ASSOCIATE A SOVRACCARICO MARZIALE (2006)	1/1/06
Caratterizzazione molecolare dell’eritropoiesi: analisi post-genomica e funzionale del profilo di espressione proteica	11/30/04
Caratterizzazione molecolare dell'eritropoiesi:analisi post-genomica e funzionale del progiloi di espressione proteica	9/30/04
Approccio proteomico funzionale ai sistemi di trasporto ionico di membrana coinvolti nella regolazione del volume cellulare e nella crescita nei precursori eritroidi: ruolo del cotrsporto K-Cl nei globuli rossi normali e beta talassemici. (2004)	1/1/04
Erythroid proteomics: clinical and therapeutic implications	1/10/03
Approccio proteomico al danno ossidativo della membrana eritrocitaria nella beta talassemia e drepanocitosi	12/16/02
Magnesium and sickle cell disease	12/1/02
Magnesium and Sickle Cell Disease	9/1/02
Studio dei determinanti genetici ed acquisti dell'ipertensione arteriosa e della progressione arteriosclerotica ad essa correlata	7/1/02
Molecular mechanisms of cell dehydration in sickle cell disease and beta thalassemia. Regulation ofK-Cl cotransport in normal and diseased erythrocytes.	7/1/99
Caratterizzazione dei sistemi di trasporto coinvolti nella regolazione del volume cellulare in patologie congenite del globulo rosso. (1999)	1/1/99
Novel Gardos channel blockers and sickled red blood cell dehydration.	11/1/98

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Lucia De Franceschi

Office	Collegial Body
	Collegio dei Docenti del Dottorato di Ricerca in Proteomica Clinica
member	Collegio dei Docenti del Dottorato in Medicina Biomolecolare A.A. 2022/2023 - Department Medicine
member	Council for the Degree Course in Dentistry and Dental Implants - Medicine and Surgery
	Consiglio del Dipartimento di Medicina - Department Medicine
	Consiglio della Scuola di specializzazione in Medicina d'emergenza-urgenza - Medicine and Surgery
	Consiglio della Scuola di Specializzazione in Medicina Interna - Medicine and Surgery
member	Consiglio per la Formazione e la Ricerca