Mauro Krampera

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Foto Prof. Krampera, July 5, 2017
Position
Full Professor
Sections
Haematology Section
Academic sector
MED/15 - BLOOD DISEASES
Research sector (ERC)
LS3_7 - Cell signalling and cellular interactions

LS3_8 - Signal transduction

LS3_12 - Stem cell biology

Telephone
0458124034
Fax
0458027488
E-mail
mauro|krampera*univr|it <== Replace | with . and * with @ to have the right email address.
Curriculum

Specialization in Hematology, Ph.D. in Experimental Hematology; Director of the Section of Hematology. Specific competence in acute leukemia, immunophenotypic monitoring of minimal residual disease and stem cell-based therapies. Winner in 2000 of the “Leonino Fontana e Maria Lionello” annual grant supporting oncological research activity abroad, assigned by Fondazione Italiana per la Ricerca sul Cancro (FIRC). Winner on 30 Nov 2009 of the Apindustria Verona Giovani Prize “Because of the important discovery of Leptomeningeal Stem Cells and the collaborative team work in research conduction”.
Since 1998, he has acquired a broad professional experience and competence, with continuous clinical activity (including night and day on-call-service and consultancy in other Hospital Units) and direct responsibility for patient management, in all the services of the Section of Hematology, University of Verona, including Inpatient Ward, Bone Marrow Transplant Unit (whose he was Responsible for Quality Assurance), Outpatient Service (Clinic and Hospital Day), and Laboratory of Hematological Diagnostics. Specific competences for diagnosis, treatment, management of complications and follow-up of hematological patients undergoing chemotherapy and autologous or allogeneic stem cell transplantation.
From 2004 he collaborates with Dr. Luc Sensebé (Etablissement Francais du Sang Centre Atlantique, Tours - Toulouse, France) to design protocols of human mesenchymal stem cells for clinical use according to the rules of GMP (Good Manufacturing Practice). Co-founder (2008-2013), with Dr. Sensebé, and member of the European Consortium CASCADE (Cultivated Adult
In 2008 he was the co-founder with Dr. Pierre Layrolle (INSERM, Nantes, France) and member of the European Consortium REBORNE (Regenerating Bone defects using New biomedical Engineering approaches), financed in 2009 by the 7TH Framework Programme on Research, Technological Development and Demonstration of European Commission.
Since 2011 he is a member of the Mesenchymal Stromal Cell (MSC) Committee of the International Society for Cellular Therapy (ISCT) while from 2013 to 2015 he is a      member of the Mesenchymal Stromal Cell (MSC) Ruler Working Group, coordinated by Prof. Armand Keating (University of Toronto, Canada)
 

Modules

Modules running in the period selected: 144.
Click on the module to see the timetable and course details.

Course Name Total credits Online Teacher credits Modules offered by this teacher
Combined Bachelor's + Master's degree in Medicine and Surgery Immunophenotyping in normal hematopoiesis and in hematological diseases (2021/2022)   1    1 
Master's degree in Molecular and Medical Biotechnology Stem cells biology (2021/2022)   6    6 
Combined Bachelor's + Master's degree in Medicine and Surgery Stem cell transplantation: biological and clinical issues (2021/2022)   1    1 
Combined Bachelor's + Master's degree in Medicine and Surgery Systematic pathology I (2021/2022)   22  eLearning 2  EMATOLOGIA
1  DIDATTICA PRATICA DI EMATOLOGIA, GASTROENTEROLOGIA, MALATTIE INFETTIVE, REUMATOLOGIA, DERMATOLOGIA E TUTORIAL PROBLEM BASED LEARNING [Gruppo Prof. Krampera] (Didattica pratica di Ematologia)
PhD in Clinical and Experimental Biomedical Sciences Attività didattica dottorato (2021/2022)   50    1.5 
Combined Bachelor's + Master's degree in Medicine and Surgery Immunophenotyping in normal hematopoiesis and in hematological diseases (2020/2021)   1  eLearning 1 
Master's degree in Molecular and Medical Biotechnology Stem cells biology (2020/2021)   6  eLearning 6 
Combined Bachelor's + Master's degree in Medicine and Surgery Stem cell transplantation: biological and clinical issues (2020/2021)   1  eLearning 1 
Combined Bachelor's + Master's degree in Medicine and Surgery Systematic pathology I (2020/2021)   22  eLearning 1  DIDATTICA PRATICA DI EMATOLOGIA, GASTROENTEROLOGIA, MALATTIE INFETTIVE, REUMATOLOGIA, DERMATOLOGIA E TUTORIAL PROBLEM BASED LEARNING [Gruppo Prof. Krampera] (Didattica pratica di Ematologia)
2  EMATOLOGIA
PhD in Clinical and Experimental Biomedical Sciences Attività didattica dottorato (2020/2021)   50  eLearning 1 
Postgraduate Specialisation in Haematology Endocrinology (2019/2020)   1    1 
Postgraduate Specialisation in Haematology Endocrinology (2019/2020)   1    1 
Postgraduate Specialisation in Paediatrics Hematology (2019/2020)   0.5    0.5 
Postgraduate Specialisation in Emergency and Urgent Medicine Hematology (2019/2020)   1    1 
Scuola di Specializzazione in Allergologia ed Immunologia Clinica (D.I. 68/2015) Hematology (2019/2020)   1     
Postgraduate Specialisation in Clinical Pathology and Clinical Biochemistry Hematology (2019/2020)   1    1 
Postgraduate Specialisation in Haematology Hematology (2019/2020)   38    2  DIDATTICA FRONTALE (Malattie del sangue Krampera Mauro)
Postgraduate Specialisation in Haematology Hematology (2019/2020)   58    2.5  DIDATTICA FRONTALE (Malattie del sangue Krampera Mauro)
Postgraduate Specialisation in Haematology Hematology (2019/2020)   57    1.33  DIDATTICA FRONTALE (Malattie del sangue Krampera Mauro)
Postgraduate Specialisation in Haematology Hematology (2019/2020)   42    0.84  DIDATTICA FRONTALE (Malattie del sangue Krampera Mauro)
Combined Bachelor's + Master's degree in Medicine and Surgery Immunophenotyping in normal hematopoiesis and in hematological diseases (2019/2020)   1  eLearning 1 
Master's degree in Molecular and Medical Biotechnology Stem cells biology (2019/2020)   6  eLearning 6 
Combined Bachelor's + Master's degree in Medicine and Surgery Stem cell transplantation: biological and clinical issues (2019/2020)   1    1 
Combined Bachelor's + Master's degree in Medicine and Surgery Systematic pathology I (2019/2020)   22  eLearning 2  EMATOLOGIA
1  DIDATTICA PRATICA DI EMATOLOGIA, GASTROENTEROLOGIA, MALATTIE INFETTIVE, REUMATOLOGIA, DERMATOLOGIA E TUTORIAL PROBLEM BASED LEARNING [Gruppo Prof. Krampera] (Didattica pratica di Ematologia)
Postgraduate Specialisation in Haematology Endocrinology (2018/2019)   1    1 
Postgraduate Specialisation in Pathological Anatomy Hematology (2018/2019)   1    1 
Postgraduate Specialisation in Haematology Hematology (2018/2019)   38    2  DIDATTICA FRONTALE (Malattie del sangue Krampera Mauro)
Postgraduate Specialisation in Haematology Hematology (2018/2019)   58    2.5  DIDATTICA FRONTALE (Malattie del sangue Krampera Mauro)
Postgraduate Specialisation in Haematology Hematology (2018/2019)   57    1.33  DIDATTICA FRONTALE (Malattie del sangue Krampera Mauro)
Postgraduate Specialisation in Haematology Hematology (2018/2019)   42    0.83  DIDATTICA FRONTALE (Malattie del sangue Krampera Mauro)
Combined Bachelor's + Master's degree in Medicine and Surgery Immunophenotyping in normal hematopoiesis and in hematological diseases (2018/2019)   1    1 
Master's degree in Molecular and Medical Biotechnology Stem cells biology (2018/2019)   6    6 
Combined Bachelor's + Master's degree in Medicine and Surgery Stem cell transplantation: biological and clinical issues (2018/2019)   1    1 
Combined Bachelor's + Master's degree in Medicine and Surgery Systematic pathology I (2018/2019)   22  eLearning 2  EMATOLOGIA
1  DIDATTICA PRATICA DI EMATOLOGIA, GASTROENTEROLOGIA, MALATTIE INFETTIVE, REUMATOLOGIA, DERMATOLOGIA E TUTORIAL PROBLEM BASED LEARNING [Gruppo Prof. Krampera] (Didattica pratica di Ematologia)
Postgraduate Specialisation in Emergency and Urgent Medicine Hematology (2017/2018)   1    1 
Postgraduate Specialisation in Internal Medicine Hematology (2017/2018)   1     
Postgraduate Specialisation in Clinical Pathology and Clinical Biochemistry Hematology (2017/2018)   1    1 
Postgraduate Specialisation in Medical Oncology Hematology (2017/2018)   1     
Postgraduate Specialisation in Pathological Anatomy Hematology (2017/2018)   1    1 
Postgraduate Specialisation in Geriatrics Hematology (2017/2018)   1     
Postgraduate Specialisation in Haematology Hematology (2017/2018)   38    2  DIDATTICA FRONTALE
Postgraduate Specialisation in Haematology Hematology (2017/2018)   58    2.5  DIDATTICA FRONTALE
Postgraduate Specialisation in Haematology Hematology (2017/2018)   57    1.33  DIDATTICA FRONTALE
Postgraduate Specialisation in Haematology Hematology (2017/2018)   42    0.83  DIDATTICA FRONTALE
Combined Bachelor's + Master's degree in Medicine and Surgery Immunophenotyping in normal hematopoiesis and in hematological diseases (2017/2018)   1    1 
Master's degree in Molecular and Medical Biotechnology Stem cells biology (2017/2018)   6    6 
Combined Bachelor's + Master's degree in Medicine and Surgery Stem cell transplantation: biological and clinical issues (2017/2018)   1    1 
Combined Bachelor's + Master's degree in Medicine and Surgery Systematic pathology I (2017/2018)   22  eLearning 1  DIDATTICA PRATICA DI EMATOLOGIA, GASTROENTEROLOGIA, MALATTIE INFETTIVE, REUMATOLOGIA, DERMATOLOGIA E TUTORIAL PROBLEM BASED LEARNING [Gruppo Prof. Krampera] (Didattica pratica di Ematologia)
1  EMATOLOGIA
Postgraduate Specialisation in Emergency and Urgent Medicine Malattie del sangue 5 (2017/2018)   1    1 
Postgraduate Specialisation in Rheumatology Malattie del sangue 5 (2017/2018)   1    1 
Postgraduate Specialisation in Endocrinology and Metabolic Diseases Malattie del sangue 5 (2017/2018)   1    1 
Postgraduate Specialisation in Medical Oncology Malattie del sangue 5 (2017/2018)   1    1 
Postgraduate Specialisation in Gastroenterology Malattie del sangue 5 (2017/2018)   1    1 
Postgraduate Specialisation in Geriatrics Malattie del sangue 5 (2017/2018)   1    1 
Postgraduate Specialisation in Haematology Malattie del sangue 5 (2017/2018)   3    1  DIDATTICA FRONTALE
Postgraduate Specialisation in Infectious Diseases Malattie del sangue 5 (2017/2018)   1    1 
Postgraduate Specialisation in Haematology Malattie del sangue 5 (discipline specifiche) (2017/2018)   36    0.5  DIDATTICA FRONTALE
Postgraduate Specialisation in Paediatrics Pediatria generale e specialistica 4 (2017/2018)   59    0.5  DIDATTICA FRONTALE (Ped. mal. sangue - Krampera)
Postgraduate Specialisation in Pathological Anatomy Hematology (2016/2017)   1    1 
Postgraduate Specialisation in Haematology Hematology (2016/2017)   38    2  DIDATTICA FRONTALE
Postgraduate Specialisation in Haematology Hematology (2016/2017)   58    2.5  DIDATTICA FRONTALE
Postgraduate Specialisation in Haematology Hematology (2016/2017)   57    1.3  DIDATTICA FRONTALE
Postgraduate Specialisation in Haematology Hematology (2016/2017)   43    0.62  DIDATTICA FRONTALE
Postgraduate Specialisation in Haematology Hematology (2016/2017)   42    0.8  DIDATTICA FRONTALE
Combined Bachelor's + Master's degree in Medicine and Surgery Immunophenotyping in normal hematopoiesis and in hematological diseases (2016/2017)   1    1 
Master's degree in Molecular and Medical Biotechnology Stem cells biology (2016/2017)   6    6 
Combined Bachelor's + Master's degree in Medicine and Surgery Stem cell transplantation: biological and clinical issues (2016/2017)   1    1 
Combined Bachelor's + Master's degree in Medicine and Surgery Systematic pathology I (2016/2017)   23  eLearning 1  DIDATTICA PRATICA DI EMATOLOGIA, GASTROENTEROLOGIA, MALATTIE INFETTIVE, REUMATOLOGIA, DERMATOLOGIA E TUTORIAL PROBLEM BASED LEARNING [Gruppo Prof. Krampera] (Didattica pratica di Ematologia)
1  EMATOLOGIA
Postgraduate Specialisation in Rheumatology Malattie del sangue 5 (2016/2017)   1    1 
Postgraduate Specialisation in Dermatology and Venereology Malattie del sangue 5 (2016/2017)   1    1 
Postgraduate Specialisation in Haematology Malattie del sangue 5 (2016/2017)   3    1  DIDATTICA FRONTALE
Postgraduate Specialisation in Endocrinology and Metabolic Diseases Malattie del sangue 5 (2016/2017)   1    1 
Postgraduate Specialisation in Gastroenterology Malattie del sangue 5 (2016/2017)   1    1 
Postgraduate Specialisation in Geriatrics Malattie del sangue 5 (2016/2017)   1    1 
Postgraduate Specialisation in Infectious Diseases Malattie del sangue 5 (2016/2017)   1    1 
Postgraduate Specialisation in Emergency and Urgent Medicine Malattie del sangue 5 (2016/2017)   1    1 
Postgraduate Specialisation in Medical Oncology Malattie del sangue 5 (2016/2017)   1    1 
Postgraduate Specialisation in Haematology Malattie del sangue 5 (discipline specifiche) (2016/2017)   36    0.5  DIDATTICA FRONTALE
Postgraduate Specialisation in Paediatrics Pediatria generale e specialistica 4 (2016/2017)   59    0.5  DIDATTICA FRONTALE
Postgraduate Specialisation in Rheumatology Endocrinology (2015/2016)   2    0.5 
Postgraduate Specialisation in Haematology Hematology (2015/2016)   38    1.5  DIDATTICA FRONTALE
Postgraduate Specialisation in Haematology Hematology (2015/2016)   58    1.5  DIDATTICA FRONTALE
Postgraduate Specialisation in Haematology Hematology (2015/2016)   51    1.25  DIDATTICA FRONTALE
Postgraduate Specialisation in Haematology Hematology (2015/2016)   42    1  DIDATTICA FRONTALE
Combined Bachelor's + Master's degree in Medicine and Surgery Immunophenotyping in normal hematopoiesis and in hematological diseases (2015/2016)   1    1 
Master's degree in Molecular and Medical Biotechnology Stem cells biology (2015/2016)   6    6 
Combined Bachelor's + Master's degree in Medicine and Surgery Stem cell transplantation: biological and clinical issues (2015/2016)   1    1 
Combined Bachelor's + Master's degree in Medicine and Surgery Systematic pathology I (2015/2016)   23  eLearning 1  EMATOLOGIA
1  DIDATTICA PRATICA DI EMATOLOGIA, GASTROENTEROLOGIA, MALATTIE INFETTIVE, REUMATOLOGIA, DERMATOLOGIA E TUTORIAL PROBLEM BASED LEARNING [Gruppo Prof. Krampera] (Didattica pratica di Ematologia)
Postgraduate Specialisation in Haematology Malattie del sangue 5 (2015/2016)   3    0.5  DIDATTICA FRONTALE
Postgraduate Specialisation in Medical Oncology Malattie del sangue 5 (2015/2016)   1    1 
Postgraduate Specialisation in Haematology Hematology (2014/2015)   38    1.5  DIDATTICA FRONTALE
Postgraduate Specialisation in Haematology Hematology (2014/2015)   58    1.5  DIDATTICA FRONTALE
Postgraduate Specialisation in Haematology Hematology (2014/2015)   51    1  DIDATTICA FRONTALE
Postgraduate Specialisation in Haematology Hematology (2014/2015)   42    1  DIDATTICA FRONTALE
Combined Bachelor's + Master's degree in Medicine and Surgery Immunophenotyping in normal hematopoiesis and in hematological diseases (2014/2015)   1    1 
Combined Bachelor's + Master's degree in Medicine and Surgery Stem cell transplantation: biological and clinical issues (2014/2015)   1    1 
Combined Bachelor's + Master's degree in Medicine and Surgery Systematic pathology I (2014/2015)   23    1  DIDATTICA PRATICA DI EMATOLOGIA, GASTROENTEROLOGIA, MALATTIE INFETTIVE, REUMATOLOGIA, DERMATOLOGIA E TUTORIAL PROBLEM BASED LEARNING [Gruppo Dott. Krampera] (Didattica pratica di Ematologia)
Postgraduate Specialisation in Medical Oncology Malattie del sangue 5 (2014/2015)   1    1 
Postgraduate Specialisation in Haematology Hematology (2013/2014)   51    1  DIDATTICA FRONTALE
Combined Bachelor's + Master's degree in Medicine and Surgery Immunophenotyping in normal hematopoiesis and in hematological diseases (2013/2014)   1    1 
Combined Bachelor's + Master's degree in Medicine and Surgery Stem cell transplantation: biological and clinical issues (2013/2014)   1    1 
Combined Bachelor's + Master's degree in Medicine and Surgery Systematic pathology I (2013/2014)   23    1  DIDATTICA PRATICA DI EMATOLOGIA, GASTROENTEROLOGIA, MALATTIE INFETTIVE, REUMATOLOGIA, DERMATOLOGIA E TUTORIAL PROBLEM BASED LEARNING [Gruppo Dott. Krampera] (Didattica pratica di Ematologia)
Postgraduate Specialisation in Haematology Malattie del sangue 5 (2013/2014)   3    0.5  DIDATTICA FRONTALE
Bachelor's degree in Biomedical Laboratory Techniques (to qualify as a biomedical laboratory worker) (Rovereto) Clinical Sciences (2012/2013)   4    1  MALATTIE DEL SANGUE
Postgraduate Specialisation in Haematology Hematology (2012/2013)   50    0.75  DIDATTICA FRONTALE
Specialist degree in Medicine and Surgery (single cycle) Immunophenotyping in normal hematopoiesis and in hematological diseases (2012/2013)   1    1 
Specialist degree in Medicine and Surgery (single cycle) Stem cell transplantation: biological and clinical issues (2012/2013)   1    1 
Combined Bachelor's + Master's degree in Medicine and Surgery Systematic pathology I (2012/2013)   23    1  DIDATTICA PRATICA DI EMATOLOGIA, GASTROENTEROLOGIA, MALATTIE INFETTIVE, REUMATOLOGIA, DERMATOLOGIA E TUTORIAL PROBLEM BASED LEARNING [Gruppo Dott. Krampera] (Didattica Pratica di Ematologia)
Bachelor's degree in Biomedical Laboratory Techniques (to qualify as a biomedical laboratory worker) (Rovereto) Clinical Sciences (2011/2012)   4    1  MALATTIE DEL SANGUE
Specialist degree in Medicine and Surgery (single cycle) Immunophenotyping in normal hematopoiesis and in hematological diseases (2011/2012)   1    1 
Specialist degree in Medicine and Surgery (single cycle) Stem cell transplantation: biological and clinical issues (2011/2012)   1    1 
Specialist degree in Medicine and Surgery (single cycle) Systematic pathology I (2011/2012)   23    0.5  ATTIVITÀ PRATICA IN EMATOLOGIA [Gruppo Dott. Krampera]
Postgraduate Specialisation in Haematology Malattie del sangue 3° anno (Didattica Frontale) (2011/2012)   6    0.75 
Specialist degree in Medicine and Surgery (single cycle) Immunophenotyping in normal hematopoiesis and in hematological diseases (2010/2011)   1    1 
Degree in Biomedical Laboratory Techniques (Rovereto) Oncology and blood disorders (2010/2011)   2    1  MALATTIE DEL SANGUE
Specialist degree in Medicine and Surgery (single cycle) Stem cell transplantation: biological and clinical issues (2010/2011)   1    1 
Specialist degree in Medicine and Surgery (single cycle) Systematic pathology I (2010/2011)   23    0.5  ATTIVITÀ PRATICA IN EMATOLOGIA [Gruppo Dott. Krampera]
Postgraduate Specialisation in Haematology Malattie del sangue 3° anno (Didattica Frontale) (2010/2011)   6    0.75 
Specialist degree in Medicine and Surgery (single cycle) Immunophenotyping in normal hematopoiesis and in hematological diseases (2009/2010)   1    1 
Degree in Biomedical Laboratory Techniques (Rovereto) Oncology and blood disorders (2009/2010)   2    1  MALATTIE DEL SANGUE
Specialist degree in Medicine and Surgery (single cycle) Stem cell transplantation: biological and clinical issues (2009/2010)   1    1 
Specialist degree in Medicine and Surgery (single cycle) Systematic pathology I (2009/2010)   23    0.5  ATTIVITÀ PRATICA IN EMATOLOGIA [Gruppo Dott. Krampera]
School of Specialisation in Haematology Ematologia clinica (III anno) (2009/2010)   96    10 
Specialist degree in Medicine and Surgery (single cycle) Immunophenotyping in normal hematopoiesis and in hematological diseases (2008/2009)   1    1 
Degree in Biomedical Laboratory Techniques (Rovereto) Oncology and blood disorders (2008/2009)   2    1  Malattie del sangue
Specialist degree in Medicine and Surgery (single cycle) Stem cell transplantation: biological and clinical issues (2008/2009)   1    1 
Specialist degree in Medicine and Surgery (single cycle) Systematic pathology I (2008/2009)   23    0.5  Attività pratica in Ematologia
School of Specialisation in Haematology Ematologia clinica (III anno) (2008/2009)   106    10 
Postgraduate Specialisation in Haematology Malattie del Sangue (didattica fontale) (2008/2009)   6    0.75 
Degree in Biomedical Laboratory Techniques (Rovereto) Oncology and blood disorders (2007/2008)   2    1  Malattie del sangue
Specialist degree in Medicine and Surgery (single cycle) Systematic pathology I (2007/2008)   23    0.5  Attività pratica in Ematologia
Degree in Biomedical Laboratory Techniques (Rovereto) Oncology and blood disorders (2006/2007)   2    1  Malattie del sangue
Specialist degree in Medicine and Surgery (single cycle) Systematic pathology I (2006/2007)   23    0.5  Attività pratica in Ematologia
Degree in Biomedical Laboratory Techniques (Rovereto) Oncology and blood disorders (2005/2006)   2    1  Malattie del sangue
Specialist degree in Medicine and Surgery (single cycle) Systematic pathology I (2005/2006)   23    0.5  Attività pratica in Ematologia
Degree in Biomedical Laboratory Techniques (Rovereto) Oncology and blood disorders (2004/2005)   2      Malattie del sangue
Specialized Degree in Medicine and Surgery (one cycle) Practical Didactics: Blood Diseases (2003/2004)   0     

 

Research groups

Laboratorio di Ricerca sulle Cellule Staminali e supporto stromale alle neoplasie ematologiche
Research interests
Topic Description Research area
Biology and clinical application of adult stem cells Biology and clinical application of adult stem cells, including: a) mesenchymal stromal cells: investigation of their differentiation potential and of their role in regenerative medicine, transplant-related immune reactions following allogeneic bone marrow transplantation, tumor-specific immune responses and stromal support to hematological and nonhematological malignancies; b) hematopoietic stem cells: in vitro expansion and in vivo transplantation; c) leukemia stem cells: study of the mechanisms of leukemia self-renewal, with particular interest in the role of the Notch and Wnt pathways in the stromal support to acute and chronic leukemia development, as potential targets for new drug development; d) neural stem cells: study of in vivo niches of neurogenesis; e) cardiac stem cells: study of the mechanisms of regeneration of infarcted myocardium; f) epithelial stem cells: study of the mechanism of wound healing and epithelial regeneration. Cell Biology
immunophenotype of acute and chronic leukemias immunophenotypic characterization of acute and chronic leukemias Hematology
immunophenotype in malignant and non-malignant conditions immunophenotypic and functional characterization and sorting of lymphoid subsets in peripheral blood and normal hemato-lymphopoietic tissues and in a number of malignant and non-malignant conditions Hematology
flow-cytometric monitoring of minimal residual disease clinical application of flow-cytometric monitoring of minimal residual disease (MRD) in acute leukemia patients; he coordinated the use of this approach also in an Italian multicentre study (GIMEMA LAL0496) Hematology
Experimental studies in leukemias, lymphomas and multiple myeloma In vitro studies on new therapeutic agents Hematology
Projects
Title Starting date
The role of bone marrow stromal extracellular vesicles in acute myeloid leukemia development 1/1/18
In vitro and in vivo characterization of bone marrow stromal extracellular vesicle-mediated promotion of acute myeloid leukemia cell chemoresistance and survival 1/1/17
Utilizzo di cellule staminali mesenchimali (MSC) da midollo osseo per la rigenerazione ossea e corneale e per l’immunoterapia della malattia da trapianto verso l’ospite (GvHD) dopo trapianto allogenico di cellule staminali emopoietiche 1/1/12
Utilizzo di cellule staminali mesenchimali (MSC) da midollo osseo per la rigenerazione ossea e corneale e per l’immunoterapia della malattia da trapianto verso l’ospite (GvHD) dopo trapianto allogenico di cellule staminali emopoietiche (I) 1/1/12
Progetto pilota per la creazione di una rete di biobanche venete a scopo di ricerca 1/1/12
Role of leptomeningeal stem cells in spinal cord injury 1/1/11
Nuovi approcci per la cura della Fibrosi Cistica mediante terapia genica e cellulare 1/1/10
Studio del ruolo fisiologico e delle potenzialità riparative delle cellule staminali da leptomeningi (Leptomeningeal Stem Cells, LeSC) nella lesione del midollo spinale 1/1/10
REBORNE (Regenerating Bone defects using New biomedical Engineering approaches) 1/1/10
Uso in vivo di cellule staminali mesenchimali (MSC) per la rigenerazione ossea in chirurgia maxillo-facciale 1/1/10
Confronto delle proprieta' immunoregolatorie di cellule staminali mesenchimali di diversa origine e di altre cellule staminali adulte 1/1/10
CASCADE (Cultivated Adult Stem Cells as Alternative for Damaged tissuE) 1/1/09
Utilizzo delle capacità rigenerative ed immunoregolatorie delle cellule staminali mesenchimali per il trattamento di patologie osse, neurologiche e cardiologiche 1/1/09
Un approccio integrato ai disordini linfoproliferativi cronici: B-CLL e neoplasie virus-correlate 1/1/08
INFLUENZA DEL MICROAMBIENTE STROMALE DERIVATO DA CELLULE STAMINALI MESENCHIMALI SULLA CRESCITA NEOPLASTICA E SULL’IMMUNITÀ INNATA E ADOTTIVA ANTI-TUMORALE (2007) 1/1/07
Influenza del microambiente stromale derivato da cellule staminali mesenchimali sulla crescita neoplastica e sull’immunità innata e adottiva anti-tumorale 1/1/07
Farmaci cellulari, vaccini e bioterapie innovative dei tumori 1/1/07
Trattamento di patologie autoimmuni neurologiche con cellule staminali mesenchimali: studio di efficacia e dei meccanismi molecolari 12/1/05
Effetto immunoregolatorio delle cellule staminali mesenchimali: caratterizzazione funzionale, bersagli cellulari e meccanismi molecolari coinvolti 9/30/05
Strategie innovative combinate per la diagnosi e la terapia del carcinoma della prostata 5/30/05
Analisi dei meccanismi coinvolti nell'effetto immunoregolatorio delle cellule staminali mesenchimali midollari umane 1/1/05
Strategie innovative combinate per la diagnosi e la terapia del tumore della prostata 1/1/05
Studio degli effetti biologici dell’Heparin Binding-Epidermal Growth Factor-like Growth Factor (HB-EGF) su cellule staminali mesenchimali midollari 1/1/05
MICROAMBIENTE E PROGRESSIONE NEOPLASTICA: IL NETWORK DI REGOLAZIONE INDOTTO DA CELLULE STROMALI. BIOLOGIA E APPLICAZIONI TERAPEUTICHE 9/1/04
Modulazione della risposta immune mediata da cellule mesenchimali umane midollari, staminali e differenziate: studio degli effettori cellulari bersaglio e delle vie inter- e intracellulari coinvolte 1/1/04
Infusione in vivo di cellule staminali mesenchimali (MSC) transfettate con geni per citochine immunoregolatorie per aumentare l'effetto immune antitumorale locale 1/1/03
Microambiente e progressione neoplastica: il network di regolazione indotto da cellule stromali. biologia e applicazioni terapeutiche 1/1/03
Espansione di linfociti citotossici anti-citomegalovirus dopo trapianto allogenico di cellule staminali emopoietiche 1/1/02
Caratterizzazione biologica e strategie terapeutiche innovative nelle malattie sistemiche dell'adulto e dell'età pediatrica. Significato clinico-prognostico dell'analisi immunofenotipica della malattia residua minima nella leucemia linfoblastica dell'adulto 1/1/02
Utilizzo di cellule mesenchimali di midollo osseo per modulare le reazioni di rigetto dopo trapianto allogenico di cellule staminali emopoietiche 1/1/01
Valutazione citofluorimetrica intracellulare della produzione di citochine in linfociti T, cellule NK e monociti di sangue di cordone ombelicale 1/1/00
L’infusione di linfociti del donatore (DLI, Donor Lymphocyte Infusion) in caso di ricaduta leucemica dopo trapianto di cellule staminali allogeniche (da midollo osseo o da sangue periferico): ruolo dei linfociti T specifici per antigeni minori di istocompatibilità nel mantenere l’effetto anti-leucemico (GvL, Graft versus Leukemia) in assenza di malattia da trapianto verso l’ospite (GvHD, Graft versus Host Disease) 1/1/00
Fattori angiogenetici nel mieloma: significato biologico e implicazioni terapeutiche e prognostiche 1/1/00
Meccanismi di controllo delle leucemie cromosoma-philadelphia positive: implicazioni e applicazioni terapeutiche. Riarrangiamenti BCR/ABL e produzione di fattori angiogenetici e anti-angiogenetici 1/1/00
Fattori angiogenici e antiangiogenici nella leucemia linfatica cronica 1/1/00
Malignant/bystander cell interactions in leukemia and lymphoma 1/1/98
CD30/CD30-Ligando, sCD30 e modulazione di SDF-1, MIP-1a RANTES, CXCR4 e CCR5 1/1/97
Significato biologico e clinico-prognostico del complesso CD30/CD30-ligando nell'infezione da HIV 1/1/96
Studio delle caratteristiche funzionali dei precursori ematopoietici primitivi del sangue periferico, midollare e di cordone ombelicale 1/1/96
Recettori cellulari e loro forme solubili: aspetti biologici e implicazioni cliniche in oncoematologia 1/1/95
Impiego di cellule staminali nella terapia dei linfomi non-Hodgkin 1/1/95
Significato biologico e clinico del dosaggio delle molecole solubili nelle neoplasie ematologiche 1/1/93
Gli anticorpi monoclonali per la valutazione diagnostica e biologica di antigeni cellulari e di molecole libere nelle leucemie e nei linfomi 1/1/93
Potenzialità diagnostiche e di previsione della risposta alla terapia di marcatori molecolari e complessi recettoriali nelle malattie linfoproliferative 1/1/99