Pubblicazioni

Autori:

Nepogodiev, Dmitri; Bhangu, Aneel; Glasbey, James C; Li, Elizabeth; Omar, Omar M; Simoes, Joana FF; Abbott, Tom EF; Alser, Osaid; Arnaud, Alexis P; Bankhead-Kendall, Brittany K; Breen, Kerry A; Cunha, Miguel F; Davidson, Giana H; Di Saverio, Salomone; Gallo, Gaetano; Griffiths, Ewen A; Gujjuri, Rohan R; Hutchinson, Peter J; Kaafarani, Haytham MA; Lederhuber, Hans; Löffler, Markus W; Mashbari, Hassan N; Minaya-Bravo, Ana; Morton, Dion G; Moszkowicz, David; Pata, Francesco; Tsoulfas, George; Venn, Mary L; Cox, Daniel; Roslani, April C; Alakaloko, Felix; de Vries, Jean-Paul PM; Aaraj, Mahmoud A; Abbott, Tom EF; Abbott, Sarah J; Abdalla, Mutwakil OM; Abdelaal, Ahmed S; Ademuyiwa, Adesoji O; Aherne, Thomas M; Ali, Osman M; Alkadeeki, Ghadah Z; Almeida, Ana C; Alrahawy, Mahmoud M; Ambler, Graeme K; Alameer, Ehab; Andreani, Stefano M; De Andrés-Asenjo, Beatriz; Antonanzas, Leyre Lopez; Aoun, Salah G; Ashoush, Fouad M; Augestad, Knut Magne; Avellana, Rocio B; Ayeni, Funbi A; Ayorinde, John OO; Babu, Bheemanakone H; Baig, Mirza MAS; Bajomo, Oreoluwa M; Baker, Olivia J; Baker, Markus P; Baldwin, Alexander J; Ban, Vin Shen; Baron, Ryan D; Barranquero, Alberto G; Barry, Conor P; DI Bartolomeo, Alessandro; Bass, Gary A; Bath, Michael F; Batjer, H Hunt; Beamish, Andrew J; Belgaumkar, Ajay P; Bence, Matthew N; Benson, Ruth A; Bernal-Sprekelsen, Juan Carlos; Bhama, Anuradha R; Bhavaraju, Avi V; Biffl, Walter L; Blundell, Chris M; Boddy, Alexander P; Borgstein, Alexander BJ; Bosanquet, David C; Bosch, Karen D; Bouhuwaish, Ahmad EM; Bozkurt, Mehmet A; Brathwaite, Collin EM; Brown, Benjamin C; Brown, Oliver D; Brown, Allison K; Buarque, Igor Lima; Bueno-Cañones, Alejandro D; Bulugma, Mustafa R; Burke, Joshua R; Byrne, Matthew HV; Cagigal-Ortega, Elima P; Callcut, Rachael A; DI Candido, Francesca; Canova, Michaela E; Carlos, William J; Caruana, Edward J; Cato, Liam D; Catton, Andrew B; Ceretti, Andrea Pisani; Chase, Thomas JG; Chiara, Francesco Di; Chowdhury, Abeed H; Chung, Eric A; Cicerchia, Pierfranco M; Clough, Ethan CS; Coleman, Natasha L; Collins, Chris G; Collins, Michelle L; Colonna, Emily T; Comini, Lara V; Coughlin, Patrick A; Cruzado, Laura Fernández-Gomez; Davidson, Brian R; Davies, Richard J; Davies, Emma J; Davis, Niall F; Dawson, Brett E; Dean, Benjamin JF; Delgado, Maria Garcia-Conde; Diaz, Jose J; Dickson, Kathryn E; Diez-Alonso, Manuel M; Dixon, Jan R; Doe, Matthew J; Drake, Thomas D; Drake, Frederick T; Duffy, John P; Dunne, Declan FJ; Dunne, Naomi JM; Durán-Muñoz-Cruzado, Virginia M; Durst, Alexander ZE; Eardley, Nicola J; Edwards, John G; Elfallal, Ahmed H; Elfiky, Mahmoud MA; Elliott, Jessie A; Emile, Sameh H; Emslie, Katy M; Endorf, Frederick W; Engel, Jamie L; Enjuto, Diego T; Etchill, Eric W; Evans, Jonathan P; Fahey, Brian A; Faria, Carlos S; Feo, Carlo V; Ferguson, Henry JM; Fernandez, Beatriz Dieguez; Fernandez, Andres Garcia; Fernández, Antonio J; Fernández-Pacheco, Borja Camacho; Fitzgerald, J Edward; Fonsi, Giovanni B; Font, Roser Farré; Fowler, Amy L; Fretwell, Kenneth R; Fructuoso, Lorena Sanchon; Fusai, Giuseppe K; Garcia, Miguel Hernandez; Garcia-Ureña, Miguel Angel; Gill, Charn K; Gisbertz, Suzanne S; Del Giudice, Roberto; Giuffrida, Maria Carmela; Di Giuseppe, Matteo; Gómez, María Fanjul; Griffiths, Ewen A; Guariglia, Claudio A; Hainsworth, Alison J; Hall, Bria J; Hall, James RW; Hammond, John S; Haqqani, Maha H; Harrison, Ewen M; Hazelton, Joshua P; van Heinsbergen, Maarten; Hill, Arnold DK; Hing, Caroline B; Hirji, Sameer A; Ho, Michael WS; Holbrook, Charlotte M; Holme, Thomas J; Hopkins, James C; Hopkinson, David N; Hossain, Fahad S; Hudson, Victoria E; Hughes, Jane L; Hwang, E. Shelley; Ibrahim, Mohamed AH; Isolani, Simone M; Jenkinson, Michael D; Jenny, Hillary E; Jeyaretna, Deva S; Jones, Robert P; Jones, Andrew P; Jonker, Pascal KC; Jönsson, Maria L; Joyce, Doireann P; Kalkwarf, Kyle J; Kamarajah, Sivesh K; El Kassas, Mohamed; Kavanagh, Dara O; Keatley,

Titolo:

Mortality and pulmonary complications in patients undergoing surgery with perioperative SARS-CoV-2 infection: an international cohort study

Anno:

2020

Tipologia prodotto:

Articolo in Rivista

Tipologia ANVUR:

Articolo su rivista

Lingua:

Inglese

Referee:

No

Nome rivista:

Lancet

ISSN Rivista:

0140-6736

N° Volume:

396

Numero o Fascicolo:

10243

Intervallo pagine:

27-38

Parole chiave:

Adult; Aged; Betacoronavirus; Coronavirus Infections; Elective Surgical Procedures; Emergency Medical Services; Female; Hospital Mortality; Humans; Male; Middle Aged; Pandemics; Pneumonia, Viral; Postoperative Complications; Respiratory Tract Diseases; Retrospective Studies; Surgical Procedures, Operative; Young Adult

Breve descrizione dei contenuti:

Background The impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on postoperative recovery needs to be understood to inform clinical decision making during and after the COVID-19 pandemic. This study reports 30-day mortality and pulmonary complication rates in patients with perioperative SARS-CoV-2 infection.Methods This international, multicentre, cohort study at 235 hospitals in 24 countries included all patients undergoing surgery who had SARS-CoV-2 infection confirmed within 7 days before or 30 days after surgery. The primary outcome measure was 30-day postoperative mortality and was assessed in all enrolled patients. The main secondary outcome measure was pulmonary complications, defined as pneumonia, acute respiratory distress syndrome, or unexpected postoperative ventilation.Findings This analysis includes 1128 patients who had surgery between Jan 1 and March 31, 2020, of whom 835 (74.0%) had emergency surgery and 280 (24.8%) had elective surgery. SARS-CoV-2 infection was confirmed preoperatively in 294 (26.1%) patients. 30-day mortality was 23.8% (268 of 1128). Pulmonary complications occurred in 577 (51.2%) of 1128 patients; 30-day mortality in these patients was 38.0% (219 of 577), accounting for 81.7% (219 of 268) of all deaths. In adjusted analyses, 30-day mortality was associated with male sex (odds ratio 1.75 [95% CI 1.28-2.40], p<0.0001), age 70 years or older versus younger than 70 years (2.30 [1.65-3.22], p<0.0001), American Society of Anesthesiologists grades 3-5 versus grades 1-2 (2.35 [1.57-3.53], p<0.0001), malignant versus benign or obstetric diagnosis (1.55 [1.01-2.39], p=0.046), emergency versus elective surgery (1.67 [1.06-2.63], p=0.026), and major versus minor surgery (1.52 [1.01-2.31], p=0.047).Interpretation Postoperative pulmonary complications occur in half of patients with perioperative SARS-CoV-2 infection and are associated with high mortality. Thresholds for surgery during the COVID-19 pandemic should be higher than during normal practice, particularly in men aged 70 years and older. Consideration should be given for postponing non-urgent procedures and promoting non-operative treatment to delay or avoid the need for surgery.

Id prodotto:

117480

Handle IRIS:

11562/1029664

ultima modifica:

15 novembre 2022

Citazione bibliografica:

Nepogodiev, Dmitri; Bhangu, Aneel; Glasbey, James C; Li, Elizabeth; Omar, Omar M; Simoes, Joana FF; Abbott, Tom EF; Alser, Osaid; Arnaud, Alexis P; Bankhead-Kendall, Brittany K; Breen, Kerry A; Cunha, Miguel F; Davidson, Giana H; Di Saverio, Salomone; Gallo, Gaetano; Griffiths, Ewen A; Gujjuri, Rohan R; Hutchinson, Peter J; Kaafarani, Haytham MA; Lederhuber, Hans; Löffler, Markus W; Mashbari, Hassan N; Minaya-Bravo, Ana; Morton, Dion G; Moszkowicz, David; Pata, Francesco; Tsoulfas, George; Venn, Mary L; Cox, Daniel; Roslani, April C; Alakaloko, Felix; de Vries, Jean-Paul PM; Aaraj, Mahmoud A; Abbott, Tom EF; Abbott, Sarah J; Abdalla, Mutwakil OM; Abdelaal, Ahmed S; Ademuyiwa, Adesoji O; Aherne, Thomas M; Ali, Osman M; Alkadeeki, Ghadah Z; Almeida, Ana C; Alrahawy, Mahmoud M; Ambler, Graeme K; Alameer, Ehab; Andreani, Stefano M; De Andrés-Asenjo, Beatriz; Antonanzas, Leyre Lopez; Aoun, Salah G; Ashoush, Fouad M; Augestad, Knut Magne; Avellana, Rocio B; Ayeni, Funbi A; Ayorinde, John OO; Babu, Bheemanakone H; Baig, Mirza MAS; Bajomo, Oreoluwa M; Baker, Olivia J; Baker, Markus P; Baldwin, Alexander J; Ban, Vin Shen; Baron, Ryan D; Barranquero, Alberto G; Barry, Conor P; DI Bartolomeo, Alessandro; Bass, Gary A; Bath, Michael F; Batjer, H Hunt; Beamish, Andrew J; Belgaumkar, Ajay P; Bence, Matthew N; Benson, Ruth A; Bernal-Sprekelsen, Juan Carlos; Bhama, Anuradha R; Bhavaraju, Avi V; Biffl, Walter L; Blundell, Chris M; Boddy, Alexander P; Borgstein, Alexander BJ; Bosanquet, David C; Bosch, Karen D; Bouhuwaish, Ahmad EM; Bozkurt, Mehmet A; Brathwaite, Collin EM; Brown, Benjamin C; Brown, Oliver D; Brown, Allison K; Buarque, Igor Lima; Bueno-Cañones, Alejandro D; Bulugma, Mustafa R; Burke, Joshua R; Byrne, Matthew HV; Cagigal-Ortega, Elima P; Callcut, Rachael A; DI Candido, Francesca; Canova, Michaela E; Carlos, William J; Caruana, Edward J; Cato, Liam D; Catton, Andrew B; Ceretti, Andrea Pisani; Chase, Thomas JG; Chiara, Francesco Di; Chowdhury, Abeed H; Chung, Eric A; Cicerchia, Pierfranco M; Clough, Ethan CS; Coleman, Natasha L; Collins, Chris G; Collins, Michelle L; Colonna, Emily T; Comini, Lara V; Coughlin, Patrick A; Cruzado, Laura Fernández-Gomez; Davidson, Brian R; Davies, Richard J; Davies, Emma J; Davis, Niall F; Dawson, Brett E; Dean, Benjamin JF; Delgado, Maria Garcia-Conde; Diaz, Jose J; Dickson, Kathryn E; Diez-Alonso, Manuel M; Dixon, Jan R; Doe, Matthew J; Drake, Thomas D; Drake, Frederick T; Duffy, John P; Dunne, Declan FJ; Dunne, Naomi JM; Durán-Muñoz-Cruzado, Virginia M; Durst, Alexander ZE; Eardley, Nicola J; Edwards, John G; Elfallal, Ahmed H; Elfiky, Mahmoud MA; Elliott, Jessie A; Emile, Sameh H; Emslie, Katy M; Endorf, Frederick W; Engel, Jamie L; Enjuto, Diego T; Etchill, Eric W; Evans, Jonathan P; Fahey, Brian A; Faria, Carlos S; Feo, Carlo V; Ferguson, Henry JM; Fernandez, Beatriz Dieguez; Fernandez, Andres Garcia; Fernández, Antonio J; Fernández-Pacheco, Borja Camacho; Fitzgerald, J Edward; Fonsi, Giovanni B; Font, Roser Farré; Fowler, Amy L; Fretwell, Kenneth R; Fructuoso, Lorena Sanchon; Fusai, Giuseppe K; Garcia, Miguel Hernandez; Garcia-Ureña, Miguel Angel; Gill, Charn K; Gisbertz, Suzanne S; Del Giudice, Roberto; Giuffrida, Maria Carmela; Di Giuseppe, Matteo; Gómez, María Fanjul; Griffiths, Ewen A; Guariglia, Claudio A; Hainsworth, Alison J; Hall, Bria J; Hall, James RW; Hammond, John S; Haqqani, Maha H; Harrison, Ewen M; Hazelton, Joshua P; van Heinsbergen, Maarten; Hill, Arnold DK; Hing, Caroline B; Hirji, Sameer A; Ho, Michael WS; Holbrook, Charlotte M; Holme, Thomas J; Hopkins, James C; Hopkinson, David N; Hossain, Fahad S; Hudson, Victoria E; Hughes, Jane L; Hwang, E. Shelley; Ibrahim, Mohamed AH; Isolani, Simone M; Jenkinson, Michael D; Jenny, Hillary E; Jeyaretna, Deva S; Jones, Robert P; Jones, Andrew P; Jonker, Pascal KC; Jönsson, Maria L; Joyce, Doireann P; Kalkwarf, Kyle J; Kamarajah, Sivesh K; El Kassas, Mohamed; Kavanagh, Dara O; Keatley,, Mortality and pulmonary complications in patients undergoing surgery with perioperative SARS-CoV-2 infection: an international cohort study «Lancet» , vol. 396 , n. 10243 , 2020 , pp. 27-38

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