Publications

Authors:

FRATTA PASINI, Anna Maria; Visco, Carlo; DALLA GRANA, Elisa; Fraenza, Costanza; Bodini, Marco; Pecori, Sara; CONTI BELLOCCHI, MARIA CRISTINA; Faccioli, Niccolò; Piralla, Antonio; Girelli, Domenico; Baldanti, Fausto; Ciccocioppo, Rachele

Title:

Life-Threatening Protein-Losing Enteropathy Due To Human Cytomegalovirus Infection Upon Immunochemotherapy

Year:

2021

Type of item:

Articolo in Rivista

Tipologia ANVUR:

Articolo su rivista

Language:

Inglese

Format:

Elettronico

Referee:

Sì

Name of journal:

ARCHIVES OF CLINICAL AND MEDICAL CASE REPORTS

ISSN of journal:

2575-9655

N° Volume:

5

Page numbers:

962-968

Keyword:

Human Cytomegalovirus; Immunochemotherapy; Mucosal viral load; Protein-losing enteropathy

Short description of contents:

Immunochemotherapy adverse events affecting the gastrointestinal tract usually consist of self-limiting nausea/ vomiting or diarrhoea, while bleeding and perforation are rare. A 42-year-old woman treated with bendamustine/ rituximab for splenic marginal zone lymphoma developed alife-threatening protein-losing enteropathy that was a diagnosis conundrum, ranging from drug-induced, immunemediated, neoplastic and infectious forms. Suspecting opportunistic viral infection but with unremarkable immunohistochemistry and peripheral blood tests, the diagnosis of Human Cytomegalovirus enteritis was made only by means of quantitative real-time polymerase chain reaction carried out on mucosal specimens. Steroid discontinuation and a prolonged course of antiviral therapy allowed the patient to overcome the critical phase and to achieve gradual normalisation of stool frequency, body mass index, laboratory tests lasting one year, while disappearance of mucosal viral load resulted soon evident. Human Cytom-egalovirus end-organ disease localised at the gastrointestinal tract is a serious condition whose prompt diagnosis and treatment prevents poor patients prognosis.

Product ID:

123889

Handle IRIS:

11562/1054276

Last Modified:

November 15, 2022

Bibliographic citation:

FRATTA PASINI, Anna Maria; Visco, Carlo; DALLA GRANA, Elisa; Fraenza, Costanza; Bodini, Marco; Pecori, Sara; CONTI BELLOCCHI, MARIA CRISTINA; Faccioli, Niccolò; Piralla, Antonio; Girelli, Domenico; Baldanti, Fausto; Ciccocioppo, Rachele, Life-Threatening Protein-Losing Enteropathy Due To Human Cytomegalovirus Infection Upon Immunochemotherapy «ARCHIVES OF CLINICAL AND MEDICAL CASE REPORTS» , vol. 5 , 2021 , pp. 962-968

Consulta la scheda completa presente nel repository istituzionale della Ricerca di Ateneo