Publications

Authors:

Furci, Antonio; Bruni, Manfredo; Geat, Davide; Colato, Chiara; Girolomoni, Giampiero; Schena, Donatella

Title:

Pyoderma gangrenosum associated with pseudo-PelgerHuët anomaly in a patient with idiopathic myelofibrosis

Year:

2022

Type of item:

Articolo in Rivista

Tipologia ANVUR:

Articolo su rivista

Language:

Inglese

Format:

Elettronico

Referee:

No

Name of journal:

DERMATOLOGY ONLINE JOURNAL

ISSN of journal:

1087-2108

Page numbers:

1-4

Keyword:

pseudo-Pelger-Huët, pyoderma gangrenosum

Short description of contents:

Pseudo-Pelger-Huët anomaly is a condition in which almost all the granulocytes are hyposegmented and/or hypogranulated. It is typically recognized in peripheral blood smears and represents a marker of several disorders, such as myeloproliferative diseases and myelodysplasia. The occurrence of the pseudoPelger-Huët anomaly in the cutaneous infiltrate of pyoderma gangrenosum is very rare. We describe the case of a 70-year-old man with idiopathic myelofibrosis who developed pyoderma gangrenosum. Histological examination showed an infiltrate consisting of granulocytic elements with features of dysmaturity and segmentation anomalies (hypo- and hypersegmented forms), suggestive of pseudo-Pelger-Huët anomaly. Methylprednisolone treatment resulted in progressive improvement of pyoderma gangrenosum.

Product ID:

131031

Handle IRIS:

11562/1082056

Last Modified:

October 30, 2024

Bibliographic citation:

Furci, Antonio; Bruni, Manfredo; Geat, Davide; Colato, Chiara; Girolomoni, Giampiero; Schena, Donatella, Pyoderma gangrenosum associated with pseudo-PelgerHuët anomaly in a patient with idiopathic myelofibrosis «DERMATOLOGY ONLINE JOURNAL» , 2022 , pp. 1-4

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