Publications

Authors:

Covidsurg, Collaborative; Gebran, Anthony; Gaitanidis, Apostolos; Argandykov, Dias; Maurer, Lydia R.; Gallastegi, Ander Dorken; Bokenkamp, Mary; Alser, Osaid; Nepogodiev, Dmitri; Bhangu, Aneel; Kaafarani, Haytham M. A.; Paiella, Salvatore; Turri, Giulia; Rattizzato, Simone; Campagnaro, Tommaso; Guglielmi, Alfredo; Pedrazzani, Corrado; Ruzzenente, Andrea; Poletto, Edoardo; Conci, Simone; Casetti, Luca; Fontana, Martina; Salvia, Roberto; Malleo, Giuseppe; Esposito, Alessandro; Landoni, Luca; De Pastena, Matteo; Bassi, Claudio; Tuveri, Massimiliano; Nobile, Sara; Marchegiani, Giovanni; Bortolasi, Luca

Title:

Mortality and pulmonary complications in emergency general surgery patients with COVID-19: A large international multicenter study

Year:

2022

Type of item:

Articolo in Rivista

Tipologia ANVUR:

Articolo su rivista

Language:

Inglese

Referee:

No

Name of journal:

THE JOURNAL OF TRAUMA AND ACUTE CARE SURGERY

ISSN of journal:

2163-0755

N° Volume:

93

Number or Folder:

1

Page numbers:

59-65

Keyword:

COVID-19; COVIDSurg; emergency surgery; mortality; pulmonary complications

Short description of contents:

OBJECTIVES: The outcomes of emergency general surgery (EGS) patients with concomitant COVID-19 infection remain unknown. With a multicenter study in 361 hospitals from 52 countries, we sought to study the mortality and pulmonary complications of COVID-19 patients undergoing EGS.METHODS: All patients 17 years or older and diagnosed preoperatively with COVID-19 between February and July 2020 were included. Emergency general surgery was defined as the urgent/emergent performance of appendectomy, cholecystectomy, or laparotomy. The main outcomes were 30-day mortality and 30-day pulmonary complications (a composite of acute respiratory distress syndrome, unexpected mechanical ventilation, or pneumonia). Planned subgroup analyses were performed based on presence of preoperative COVID-related respiratory findings (e.g., cough, dyspnea, need for oxygen therapy, chest radiology abnormality).RESULTS: A total of 1,045 patients were included, of which 40.1% were female and 50.0% were older than 50 years; 461 (44.1%), 145 (13.9%), and 439 (42.0%) underwent appendectomy, cholecystectomy, and laparotomy, respectively. The overall mortality ratewas 15.1% (158 of 1,045 patients), and the overall pulmonary complication rate was 32.9% (344 of 1,045 patients); in the subgroup of laparotomy patients, the rates were 30.6% (134 of 438 patients) and 59.2% (260 of 439 patients), respectively. Subgroup analyses found mortality and pulmonary complication risk to be especially increased in patients with preoperative respiratory findings.CONCLUSION: COVID-19 patients undergoing EGS have significantly high rates of mortality and pulmonary complications, but the risk is most pronounced in those with preoperative respiratory findings. Copyright (C) 2022 Wolters Kluwer Health, Inc. All rights reserved.

Product ID:

131092

Handle IRIS:

11562/1082268

Last Modified:

February 29, 2024

Bibliographic citation:

Covidsurg, Collaborative; Gebran, Anthony; Gaitanidis, Apostolos; Argandykov, Dias; Maurer, Lydia R.; Gallastegi, Ander Dorken; Bokenkamp, Mary; Alser, Osaid; Nepogodiev, Dmitri; Bhangu, Aneel; Kaafarani, Haytham M. A.; Paiella, Salvatore; Turri, Giulia; Rattizzato, Simone; Campagnaro, Tommaso; Guglielmi, Alfredo; Pedrazzani, Corrado; Ruzzenente, Andrea; Poletto, Edoardo; Conci, Simone; Casetti, Luca; Fontana, Martina; Salvia, Roberto; Malleo, Giuseppe; Esposito, Alessandro; Landoni, Luca; De Pastena, Matteo; Bassi, Claudio; Tuveri, Massimiliano; Nobile, Sara; Marchegiani, Giovanni; Bortolasi, Luca, Mortality and pulmonary complications in emergency general surgery patients with COVID-19: A large international multicenter study «THE JOURNAL OF TRAUMA AND ACUTE CARE SURGERY» , vol. 93 , n. 1 , 2022 , pp. 59-65

Consulta la scheda completa presente nel repository istituzionale della Ricerca di Ateneo