Publications

Authors:

Bolzan, Bruna; Morani, Giovanni; Rizzati, Vanni; Zamboni, Mauro; Mazzali, Gloria; Franzese, Ilaria; Tomasi, Luca; Mugnai, Giacomo; De Manna, Davide; Benfari, Giovanni; De Caro, Annamaria; Cortinovis, Matteo; Faggian, Giuseppe; Luciani, Giovanni Battista; Ribichini, Flavio Luciano

Title:

Correlation between epicardial adipose tissue and atrial fibrillation burden in coronary artery bypass graft surgery

Year:

2023

Type of item:

Articolo in Rivista

Tipologia ANVUR:

Articolo su rivista

Language:

Inglese

Referee:

No

Name of journal:

JOURNAL OF CARDIOVASCULAR MEDICINE (HAGERSTOWN, MD.)

ISSN of journal:

1558-2027

N° Volume:

24

Number or Folder:

4

Page numbers:

253-260

Keyword:

atrial fibrillation , atrial fibrillation postcoronary artery bypass graft , cardiac surgery , epicardial adipose tissue , postoperative atrial fibrillation

Short description of contents:

Aims: Recent studies suggest an association between epicardial adipose tissue (EAT) and atrial fibrillation. The aim of the study is to evaluate the quantitative and qualitative characteristics of EAT in relation to atrial fibrillation burden after coronary artery bypass graft (CABG). Methods: This prospective single-centre study included patients undergoing CABG. The patients underwent transthoracic echocardiography and collection of a bioptic sample containing right appendage and EAT during CABG for histological characterization. After surgery, clinical and telemetry data were collected. Results: Fifty-six consecutive patients were enrolled. The mean postsurgical hospitalization was 7.9 ± 3.7 days. Twenty-two patients had at least one episode of atrial fibrillation. In the atrial fibrillation group, there was a bigger atrial volume, a higher degree of diastolic disfunction, a thicker layer of EAT and an older median age in comparison with the group that did not develop it. EAT with a cut-off of 4 mm was a predictor of atrial fibrillation with an odds ratio (OR) of 1.49 (confidence interval (CI) 1.09-2.04), 73% of sensibility and 89% of specificity. From the histological analyses, the patients with atrial fibrillation had a significantly higher percentage of fibrosis. At univariate analysis, atrial volume [OR 1.05, CI 1.01-1.09, P = 0.022], E/A rate (OR 0.04, CI 0.02-0.72 P = 0.29), the percentage of fibrosis (OR 1.12, CI 1.00-1.25, P = 0.045) and age (OR 1.17, CI 1.07-1.28, P = 0.001) were predictors of atrial fibrillation. At multivariate analysis, atrial volume (P = 0.027), fibrosis (P = 0.003) and age (P = 0.039) were independent predictors of atrial fibrillation. Conclusion: Postcardiac surgical atrial fibrillation is frequent. EAT thickness, atrial volume, fibrosis and age are predictors of postcardiac surgical atrial fibrillation.

Product ID:

133098

Handle IRIS:

11562/1090066

Last Modified:

April 1, 2023

Bibliographic citation:

Bolzan, Bruna; Morani, Giovanni; Rizzati, Vanni; Zamboni, Mauro; Mazzali, Gloria; Franzese, Ilaria; Tomasi, Luca; Mugnai, Giacomo; De Manna, Davide; Benfari, Giovanni; De Caro, Annamaria; Cortinovis, Matteo; Faggian, Giuseppe; Luciani, Giovanni Battista; Ribichini, Flavio Luciano, Correlation between epicardial adipose tissue and atrial fibrillation burden in coronary artery bypass graft surgery «JOURNAL OF CARDIOVASCULAR MEDICINE (HAGERSTOWN, MD.)» , vol. 24 , n. 4 , 2023 , pp. 253-260

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