Publications

Authors:

Marino, Andrea; Campanella, Edoardo; Stracquadanio, Stefano; Calvo, Maddalena; Migliorisi, Giuseppe; Nicolosi, Alice; Cosentino, Federica; Marletta, Stefano; Spampinato, Serena; Prestifilippo, Pamela; Stefani, Stefania; Cacopardo, Bruno; Nunnari, Giuseppe

Title:

Ceftazidime/Avibactam and Meropenem/Vaborbactam for the Management of Enterobacterales Infections: A Narrative Review, Clinical Considerations, and Expert Opinion

Year:

2023

Type of item:

Articolo in Rivista

Tipologia ANVUR:

Articolo su rivista

Language:

Inglese

Referee:

No

Name of journal:

ANTIBIOTICS

ISSN of journal:

2079-6382

N° Volume:

12

Number or Folder:

10

Page numbers:

1521-1538

Keyword:

Gram-negative infections; carbapenem-resistant Enterobacterales; carbapenemases; ceftazidime–avibactam; meropenem–vaborbactam; new BL/BLICs

Short description of contents:

: This comprehensive review examines the unique attributes, distinctions, and clinical implications of ceftazidime-avibactam (CAZ-AVI) and meropenem-vaborbactam (MEM-VAB) against difficult-to-treat Enterobacterales infections. Our manuscript explores these antibiotics' pharmacokinetic and pharmacodynamic properties, antimicrobial activities, in vitro susceptibility testing, and clinical data. Moreover, it includes a meticulous examination of comparative clinical and microbiological studies, assessed and presented to provide clarity in making informed treatment choices for clinicians. Finally, we propose an expert opinion from a microbiological and a clinical point of view about their use in appropriate clinical settings. This is the first review aiming to provide healthcare professionals with valuable insights for making informed treatment decisions when combating carbapenem-resistant pathogens.

Product ID:

136283

Handle IRIS:

11562/1114326

Last Modified:

October 12, 2024

Bibliographic citation:

Marino, Andrea; Campanella, Edoardo; Stracquadanio, Stefano; Calvo, Maddalena; Migliorisi, Giuseppe; Nicolosi, Alice; Cosentino, Federica; Marletta, Stefano; Spampinato, Serena; Prestifilippo, Pamela; Stefani, Stefania; Cacopardo, Bruno; Nunnari, Giuseppe, Ceftazidime/Avibactam and Meropenem/Vaborbactam for the Management of Enterobacterales Infections: A Narrative Review, Clinical Considerations, and Expert Opinion «ANTIBIOTICS» , vol. 12 , n. 10 , 2023 , pp. 1521-1538

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