Publications

Authors:

Tamarozzi, Francesca; Ursini, Tamara; Stroffolini, Giacomo; Badona Monteiro, Geraldo; Buonfrate, Dora; Fittipaldo, Veronica Andrea; Conci, Simone; Gasparini, Clizia; Mansueto, Giancarlo; Guglielmi, Alfredo; Gobbi, Federico

Title:

Transjugular intrahepatic portosystemic shunt followed by splenectomy for complicated hepatosplenic schistosomiasis: a case report and review of the literature

Year:

2024

Type of item:

Articolo in Rivista

Tipologia ANVUR:

Articolo su rivista

Language:

Inglese

Format:

Elettronico

Referee:

No

Name of journal:

Lancet Infectious Diseases

ISSN of journal:

1473-3099

N° Volume:

24

Number or Folder:

6

Page numbers:

405-414

Keyword:

Hepatosplenic schistosomiasis

Short description of contents:

: Hepatosplenic schistosomiasis is a complex clinical condition caused by the complications of chronic infection with Schistosoma species that cause intestinal schistosomiasis. Hepatosplenic schistosomiasis derives from the fibrotic reaction stimulated around parasite eggs that are transported by the mesenteric circulation to the liver, causing periportal fibrosis. Portal hypertension and variceal gastrointestinal bleeding are major complications of hepatosplenic schistosomiasis. The clinical management of hepatosplenic schistosomiasis is not standardised and a parameter that could guide clinical decision making has not yet been identified. Transjugular intrahepatic portosystemic shunt (TIPS) appears promising for use in hepatosplenic schistosomiasis but is still reported in very few patients. In this Grand Round, we report one patient with hepatosplenic schistosomiasis treated with TIPS, which resulted in regression of oesophageal varices but had to be followed by splenectomy due to persisting severe splenomegaly and thrombocytopenia. We summarise the main challenges in the clinical management of this patient with hepatosplenic schistosomiasis, highlight results of a scoping review of the literature, and evaluate the use of of TIPS in patients with early hepatosplenic schistosomiasis, to improve the prognosis.

Note:

Epub 2024 Feb 15

Product ID:

137912

Handle IRIS:

11562/1119672

Last Modified:

January 24, 2025

Bibliographic citation:

Tamarozzi, Francesca; Ursini, Tamara; Stroffolini, Giacomo; Badona Monteiro, Geraldo; Buonfrate, Dora; Fittipaldo, Veronica Andrea; Conci, Simone; Gasparini, Clizia; Mansueto, Giancarlo; Guglielmi, Alfredo; Gobbi, Federico, Transjugular intrahepatic portosystemic shunt followed by splenectomy for complicated hepatosplenic schistosomiasis: a case report and review of the literature «Lancet Infectious Diseases» , vol. 24 , n. 6 , 2024 , pp. 405-414

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