Publications

Authors:

Brigenti, Noemi; Gisondi, Paolo; Bellinato, Francesco; Girolomoni, Giampiero

Title:

Generalized pustular psoriasis successfully treated with spesolimab: A case report

Year:

2024

Type of item:

Articolo in Rivista

Tipologia ANVUR:

Articolo su rivista

Language:

Inglese

Referee:

No

Name of journal:

SAGE OPEN MEDICAL CASE REPORTS

ISSN of journal:

2050-313X

Page numbers:

1-4

Keyword:

Generalized pustular psoriasis, IL-36, spesolimab, Generalized Pustular Psoriasis Physician Global Assessment

Short description of contents:

Generalized pustular psoriasis is defined as a primary, sterile, macroscopically visible pustular eruption on non-acral skin, which can occur with or without systemic inflammation and/or psoriasis vulgaris, and can either be relapsing or be persistent, according to the European Rare and Severe Psoriasis Expert Network. The treatment of generalized pustular psoriasis may be challenging. We describe a 48-year-old woman with a 15-year history of severe generalized pustular psoriasis and plaque psoriasis resistant to multiple courses of treatments with conventional and biological agents who had a rapid, complete and durable (up to 12 months) clinical remission with spesolimab, an anti-interleukin-36 receptor antagonist monoclonal antibody recently approved for the treatment of generalized pustular psoriasis flares.

Product ID:

138211

Handle IRIS:

11562/1120826

Last Modified:

October 31, 2024

Bibliographic citation:

Brigenti, Noemi; Gisondi, Paolo; Bellinato, Francesco; Girolomoni, Giampiero, Generalized pustular psoriasis successfully treated with spesolimab: A case report «SAGE OPEN MEDICAL CASE REPORTS» , 2024 , pp. 1-4

Consulta la scheda completa presente nel repository istituzionale della Ricerca di Ateneo