Publications

Authors:

Belli, Roberta; Dattolo, Anna; Sampogna, Francesca; Gubinelli, Emanuela; Lulli, Daniela; Moretta, Gaia; Scala, Emanuele; Sanna, Luca; Megna, Matteo; Vittoria Cannizzaro, Maria; Parisi, Melania; Luordi, Cecilia; Scarponi, Claudia; Quaranta, Maria; Grazia Lolli, Maria; Silvestri, Lorena; Gisondi, Paolo; Girolomoni, Giampiero; Pallotta, Sabatino; Albanesi, Cristina; Mercurio, Laura; Madonna, Stefania

Title:

Leptin: a gender and obesity-related marker predictive of metabolic comorbidities and therapeutic response to anti-IL-23 biologic drugs in psoriatic patients

Year:

2025

Type of item:

Articolo in Rivista

Tipologia ANVUR:

Articolo su rivista

Language:

Inglese

Referee:

No

Name of journal:

FRONTIERS IN IMMUNOLOGY

ISSN of journal:

1664-3224

Page numbers:

1-20

Keyword:

psoriasis, obesity, adipokines, anti-IL-17 biologics, anti-IL-23 biologics, gender

Short description of contents:

Psoriasisisachronicimmune-mediated inflammatory skin disorder, frequently associated with comorbidities such as obesity, which can exacerbate its severity and hinder treatment efficacy. Psoriasis pathogenesis involves complex interactions among genetic, environmental, hormonal factors, and is characterized by dysregulated immune responses. In this study, we investigated the relationship between obesity and psoriasis, exploring the impact of circulating levels of adipokines on disease severity, comorbidities, and treatment response to anti-IL-17 and anti-IL-23 biologics.

Product ID:

146742

Handle IRIS:

11562/1167109

Last Modified:

July 23, 2025

Bibliographic citation:

Belli, Roberta; Dattolo, Anna; Sampogna, Francesca; Gubinelli, Emanuela; Lulli, Daniela; Moretta, Gaia; Scala, Emanuele; Sanna, Luca; Megna, Matteo; Vittoria Cannizzaro, Maria; Parisi, Melania; Luordi, Cecilia; Scarponi, Claudia; Quaranta, Maria; Grazia Lolli, Maria; Silvestri, Lorena; Gisondi, Paolo; Girolomoni, Giampiero; Pallotta, Sabatino; Albanesi, Cristina; Mercurio, Laura; Madonna, Stefania, Leptin: a gender and obesity-related marker predictive of metabolic comorbidities and therapeutic response to anti-IL-23 biologic drugs in psoriatic patients «FRONTIERS IN IMMUNOLOGY» , 2025 , pp. 1-20

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