Publications

Authors:

G. Semenzato; A. Cipriani; L. Trentin; R. Zambello; M. Masciarelli; F. Vinante; M. Chilosi; G. Pizzolo

Title:

High serum levels of soluble interleukin-2 receptors in sarcoidosis

Year:

1987

Type of item:

Articolo in Rivista

Tipologia ANVUR:

Articolo su rivista

Language:

Inglese

Referee:

Sì

Name of journal:

Sarcoidosis

ISSN of journal:

0393-1447

N° Volume:

4

Page numbers:

25-7

Short description of contents:

We provide evidence that high levels of soluble interleukin-2 receptor (sIL-2R) are present in the serum of patients with sarcoidosis. Because sIL-2R is capable of binding to its ligand (IL-2), the increased serum levels of this molecule could induce a starvation of IL-2. This mechanism could help to explain a number of immunological abnormalities extensively reported in these patients and generally attributed to not yet identified serum inhibitory factors.

Product ID:

2163

Handle IRIS:

11562/2163

Bibliographic citation:

G. Semenzato; A. Cipriani; L. Trentin; R. Zambello; M. Masciarelli; F. Vinante; M. Chilosi; G. Pizzolo, High serum levels of soluble interleukin-2 receptors in sarcoidosis «Sarcoidosis» , vol. 4 , 1987 , pp. 25-7

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