Primary extranodal lymphomas of Waldeyer's ring, stage IE and IIE: Long-term survival after chemotherapy combined with radiotherapy
Year:
1996
Type of item:
Articolo in Rivista
Tipologia ANVUR:
Articolo su rivista
Nations of authors:
ITALIA
Language:
Inglese
Format:
A Stampa
Referee:
Sì
Name of journal:
International Journal of Oncology
ISSN of journal:
1019-6439
N° Volume:
9
Number or Folder:
4
Page numbers:
777-780
Keyword:
therapy, primary non-Hodgkin's lymphoma, Waldeyer's ring
Short description of contents:
We reviewed 45 cases of Waldeyer's ring lymphomas (25 stage IE, 20 IIE): 73% had high-grade histology according to Kiel's classification. Fourteen patients received radiotherapy alone and 31 chemotherapy, combined with radiotherapy in 28. Complete remission rate was 95% and relapse rate 32%. At 8 years overall disease-related survival (DRS) and event-free survival (EFS) were 69% and 57% respectively. Combined treatment provided both significantly better DRS (82% vs 42%) and EFS (76% vs 25%) than radiotherapy alone. Most of the patients with high-grade histology (26/33) received the combined treatment and this subgroup achieved a long-term EFS of 78%. Both DRS and EFS were also significantly longer in patients under 60. At multivariate analysis favorable prognostic factors were lower age for DRS and combined treatment for EFS.
Product ID:
819
Handle IRIS:
11562/819
Deposited On:
July 30, 2008
Last Modified:
November 2, 2016
Bibliographic citation:
F. Pasini; M. A. Bassetto; G. Todeschini; A. Dis Marco; G. Verlato; F. Scognamiglio; R. Zanotti; D. Veneri; G. L. Cetto; A. Ambrosetti,
Primary extranodal lymphomas of Waldeyer's ring, stage IE and IIE: Long-term survival after chemotherapy combined with radiotherapy«International Journal of Oncology»
, vol. 9
, n. 4
, 1996
, pp. 777-780