Publications

Authors:

Innamorati, Giulio; Valenti, Maria Teresa; Giacomello, Luca; DALLE CARBONARE, Luca Giuseppe; Bassi, Claudio

Title:

GNAS Mutations: Drivers or Co-Pilots? Yet, Promising Diagnostic Biomarkers

Year:

2016

Type of item:

Articolo in Rivista

Tipologia ANVUR:

Articolo su rivista

Language:

Inglese

Format:

A Stampa

Referee:

No

Name of journal:

trends in cancer

ISSN of journal:

2405-8033

N° Volume:

2

Number or Folder:

6

Page numbers:

282-285

Keyword:

pancreas, GNAS mutations

Short description of contents:

Over 25 years ago, GNAS mutations were discovered associated with McCune-Albright syndrome (MAS) and pituitary tumors. The mutant gene, encoding the heterotrimeric Gs protein, was named 'derived from Gs Protein' (gsp) oncogene. For a long time, gsp remained associated with specific endocrine tumors. Recently, high frequencies of gsp were reported for a rapidly growing number of neoplasms in the gastrointestinal tract. Will heterotrimeric G-proteins follow small G-proteins and become recognized as cancer biomarkers and therapeutic targets?

Product ID:

93215

Handle IRIS:

11562/949580

Last Modified:

November 15, 2022

Bibliographic citation:

Innamorati, Giulio; Valenti, Maria Teresa; Giacomello, Luca; DALLE CARBONARE, Luca Giuseppe; Bassi, Claudio, GNAS Mutations: Drivers or Co-Pilots? Yet, Promising Diagnostic Biomarkers «trends in cancer» , vol. 2 , n. 6 , 2016 , pp. 282-285

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