Publications

Authors:

Ciccarese, Chiara; Ferrara, Roberto; Fantinel, Emanuela; Zecchetto, Camilla; Simionato, Francesca; Grego, Elisabetta; Ortolani, Silvia; Caccese, Mario; Bimbatti, Davide; Cingarlini, Sara; Brunelli, Matteo; Andreini, Angelo; Tortora, Giampaolo; Massari, Francesco

Title:

Acquired hemophagocytic syndrome in a patient with synovial sarcoma: a case report

Year:

2015

Type of item:

Articolo in Rivista

Tipologia ANVUR:

Articolo su rivista

Language:

Inglese

Format:

Elettronico

Referee:

Sì

Name of journal:

FUTURE SCIENCE OA

ISSN of journal:

2056-5623

N° Volume:

1

Number or Folder:

4

Page numbers:

FSO29-FSO29

Keyword:

chemotherapy; hemophagocytic lymphohistiocytosis syndrome; synovial sarcoma

Short description of contents:

Hemophagocytic lymphohistiocytosis (HLH) is a syndrome characterized by severe hyperinflammation due to an overwhelming ineffective immune response to different triggers. Most important symptoms are fever, hepatosplenomegaly and cytopenias. Biochemical signs include elevated ferritin, hypertriglyceridemia and low fibrinogen. Hemophagocytosis in the bone marrow is a hallmark of this syndrome. Based on the pathogenetic mechanism, it can be classified into primary (inherited) or secondary (acquired) HLH. We report, to our knowledge, the first case of acquired hemophagocytic syndrome that arose in a 20-year-old man affected by synovial sarcoma as a complication during chemotherapy.

Product ID:

95542

Handle IRIS:

11562/957337

Last Modified:

November 15, 2022

Bibliographic citation:

Ciccarese, Chiara; Ferrara, Roberto; Fantinel, Emanuela; Zecchetto, Camilla; Simionato, Francesca; Grego, Elisabetta; Ortolani, Silvia; Caccese, Mario; Bimbatti, Davide; Cingarlini, Sara; Brunelli, Matteo; Andreini, Angelo; Tortora, Giampaolo; Massari, Francesco, Acquired hemophagocytic syndrome in a patient with synovial sarcoma: a case report «FUTURE SCIENCE OA» , vol. 1 , n. 4 , 2015 , pp. FSO29-FSO29

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