Publications

Authors:

Carbone, C; Piro, G; Gaianigo, Nicola; Ligorio, F; Santoro, R; Merz, V; Simionato, F; Zecchetto, C; Falco, G; Conti, G; Kamga, P. T; Krampera, M; Di Nicolantonio, F; De Franceschi, L; Scarpa, A; Tortora, G; Melisi, D.

Title:

Adipocytes sustain pancreatic cancer progression through a non-canonical WNT paracrine network inducing ROR2 nuclear shuttling

Year:

2018

Type of item:

Articolo in Rivista

Tipologia ANVUR:

Articolo su rivista

Language:

Inglese

Referee:

No

Name of journal:

International Journal of Obesity

ISSN of journal:

0307-0565

N° Volume:

42

Number or Folder:

3

Page numbers:

334-343

Keyword:

:BODY-MASS INDEX; STEM-CELLS; OBESITY; RESISTANCE; RISK; MICROENVIRONMENT; ADENOCARCINOMA; METAANALYSIS; EXPRESSION; THERAPY

Short description of contents:

Solid epidemiological evidences connect obesity with incidence, stage, and survival in pancreatic cancer. However, the underlying mechanistic basis linking adipocytes to pancreatic cancer progression remain largely elusive. We hypothesized that factors secreted by adipocytes could be responsible for epithelial-to-mesenchymal transition (EMT) induction and, in turn, a more aggressive phenotype in models of pancreatic preneoplastic lesions.

Product ID:

99459

Handle IRIS:

11562/970435

Last Modified:

November 6, 2025

Bibliographic citation:

Carbone, C; Piro, G; Gaianigo, Nicola; Ligorio, F; Santoro, R; Merz, V; Simionato, F; Zecchetto, C; Falco, G; Conti, G; Kamga, P. T; Krampera, M; Di Nicolantonio, F; De Franceschi, L; Scarpa, A; Tortora, G; Melisi, D., Adipocytes sustain pancreatic cancer progression through a non-canonical WNT paracrine network inducing ROR2 nuclear shuttling «International Journal of Obesity» , vol. 42 , n. 3 , 2018 , pp. 334-343

Consulta la scheda completa presente nel repository istituzionale della Ricerca di Ateneo