Publications

Authors:

Duarte Garcés, Alvaro A; Andrianello, Stefano; Marchegiani, Giovanni; Piccolo, Roberta; Secchettin, Erica; Paiella, Salvatore; Malleo, Giuseppe; Salvia, Roberto; Bassi, Claudio

Title:

Reappraisal of post-pancreatectomy hemorrhage (PPH) classifications: do we need to redefine grades A and B?

Year:

2018

Type of item:

Articolo in Rivista

Tipologia ANVUR:

Articolo su rivista

Language:

Inglese

Referee:

No

Name of journal:

HPB

ISSN of journal:

1365-182X

N° Volume:

20

Number or Folder:

8

Page numbers:

702-707

Keyword:

Pancreatectomy; hemorrhage

Short description of contents:

Background: Post-pancreatectomy hemorrhage (PPH) remains a major complication. The aim of this study was to reappraise the International Study Group of Pancreatic Surgery (ISGPS) classification. Methods: The clinical utility of the ISGPS classification was tested on consecutive pancreatic resections performed at the Pancreas Institute of the University of Verona Hospital. Results: PPH occurred in 65 of the 2429 patients (6.8%) undergoing pancreatic resection. Outcome of patients without PPH and with grade A PPH were comparable in terms of mortality, length of stay, ICU stay and readmission. Patients with grade B late and mild and grade B early and severe PPH had similar hospital stay and mortality rates, but differed in relaparotomy rate (10.1 vs. 81.2%, p < 0.01). Replacing “time of PPH onset” criterion with post-operative pancreatic fistula (POPF), severe PPH alone, mild PPH/POPF and severe PPH/POPF differed significantly for hospital stay (14 vs. 23 vs. 35 days, p < 0.01) and mortality rate (0 vs. 4 vs. 25%, p = 0.05). Conclusion: Grade A PPH shared the same outcome of patients without PPH. Grade B PPH included two categories of patients with different treatment modalities. The use of “concomitant POPF” instead of “time of onset” segregated three discrete categories that differed significantly in terms of clinical outcomes and management.

Product ID:

100902

Handle IRIS:

11562/973745

Last Modified:

December 1, 2022

Bibliographic citation:

Duarte Garcés, Alvaro A; Andrianello, Stefano; Marchegiani, Giovanni; Piccolo, Roberta; Secchettin, Erica; Paiella, Salvatore; Malleo, Giuseppe; Salvia, Roberto; Bassi, Claudio, Reappraisal of post-pancreatectomy hemorrhage (PPH) classifications: do we need to redefine grades A and B? «HPB» , vol. 20 , n. 8 , 2018 , pp. 702-707

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