Sezary syndrome with large cell
transformation and T-follicular
helper phenotype
Anno:
2025
Tipologia prodotto:
Articolo in Rivista
Tipologia ANVUR:
Articolo su rivista
Lingua:
Inglese
Referee:
No
Nome rivista:
JAAD CASE REPORTS
ISSN Rivista:
2352-5126
Intervallo pagine:
101-104
Parole chiave:
large cell transformation; Sezary syndrome; TFH phenotype.
Breve descrizione dei contenuti:
T-follicular helper (TFH) phenotype can be
observed in different lymphoproliferative disorders,
including angioimmunoblastic T-cell lymphoma,
mycosis fungoides1 primary cutaneous cluster of
differentiation (CD)41 small-/medium-sized pleo-
morphic lymphoproliferative disorder,2 and Sezary
syndrome (SS), apparently without any evidence of
prognostic significance.3 The TFH markers expres-
sion has been previously reported in SS,4 but to our
knowledge, SS with large cell transformation and
complete TFH phenotype has never been described.