Pubblicazioni

Autori:

Ruscitti, Piero; Vitale, Antonio; Di Cola, Ilenia; Caggiano, Valeria; Palumbo, Pierpaolo; Di Cesare, Ernesto; Hinojosa-Azaola, Andrea; Torres-Ruiz, Jiram; Guaracha-Basañez, Guillermo Arturo; Martín-Nares, Eduardo; Lopalco, Giuseppe; Morrone, Maria; Iannone, Florenzo; Giardini, Henrique A Mayrink; Cordeiro, Rafael Alves; de Brito Antonelli, Isabele Parente; Berardicurti, Onorina; Navarini, Luca; Ciccia, Francesco; Visconti, Maria Chiara; Iacono, Daniela; Direskeneli, Haner; Erten, Sukran; Yao, Haihong; Thabet, Maissa; Tharwat, Samar; Ragab, Gaafar; Gómez-Caverzaschi, Verónica; Sfikakis, Petros P; Fotis, Lampros; La Torre, Francesco; Maier, Armin; Karamanakos, Anastasios; Almaghlouth, Ibrahim A; Frassi, Micol; Tufan, Abdurrahman; Govoni, Marcello; Sota, Jurgen; Simonini, Gabriele; Emmi, Giacomo; Li Gobbi, Francesca; Parronchi, Paola; Costi, Stefania; Sarzi-Puttini, Piercarlo; Opris-Belinski, Daniela; Sfriso, Paolo; Tarsia, Maria; Maggio, Maria Cristina; Monti, Sara; Gündüz, Özgül Soysal; Rigante, Donato; Bartoloni, Elena; Verrecchia, Elena; Iagnocco, Annamaria; Viapiana, Ombretta; Bargagli, Elena; Batu, Ezgi D; Sebastiani, Gian Domenico; Del Giudice, Emanuela; Conti, Giovanni; Breda, Luciana; Gidaro, Antonio; Gicchino, Maria Francesca; Gaggiano, Carla; Brucato, Antonio Luca; Triggianese, Paola; Makowska, Joanna; Carubbi, Francesco; Farina, Nicola; Guggino, Giuliana; De Paulis, Amato; Mazzei, Maria Antonietta; Di Meglio, Nunzia; Lo Gullo, Alberto; Conforti, Alessandro; Ogunjimi, Benson; Calabrese, Laura; Rubegni, Pietro; Giardina, Annarita; Wiesik-Szewczyk, Ewa; Balistreri, Alberto; Fabiani, Claudia; Frediani, Bruno; Dagna, Lorenzo; Giacomelli, Roberto; Cantarini, Luca

Titolo:

The clinical assessment of lung involvement in patients with Still's disease, results from the multicentre international AIDA Network Still's Disease Registry

Anno:

2025

Tipologia prodotto:

Articolo in Rivista

Tipologia ANVUR:

Articolo su rivista

Lingua:

Inglese

Referee:

No

Nome rivista:

Rheumatology

ISSN Rivista:

1462-0324

Editore:

Oxford University Press

Intervallo pagine:

1-5

Parole chiave:

Still’s disease; adult-onset Still’s disease; lung involvement; prognosis; systemic juvenile idiopathic arthritis

Breve descrizione dei contenuti:

Objectives To assess the lung involvement in patients with Still's disease, an inflammatory disease assessing both children and adults. To exploit possible associated factors for parenchymal lung involvement in these patients.Methods A multicentre observational study was arranged assessing consecutive patients with Still's disease characterized by the lung involvement among those included in the AIDA (AutoInflammatory Disease Alliance) Network Still's Disease Registry. Still's disease-lung involvement was defined by the presence of pleuritis, parenchymal features, acute respiratory distress syndrome (ARDS) and/or pulmonary arterial hypertension.Results In total, 90 patients with Still's disease and lung involvement were assessed (mean age 36.3 +/- 17.8 years, 35.6% male sex). Among them, 13.3% of patients were paediatrics. These patients with lung involvement mainly showed pleuritis in 72.2% of cases, parenchymal features in 34.4%, ARDS in 9.5% and pulmonary arterial hypertension in 2.3%. After that we focused on patients characterised by parenchymal lung involvement, which is an emergent issue of clinical concern. These patients with parenchymal lung disease were significantly characterized by sore throat, pericarditis and higher values of systemic score than others. Finally, the administration of both IL-1 or IL-6 inhibitors was not associated with the presence of parenchymal lung involvement.Conclusion The clinical characteristics of patients with Still's disease and lung involvement were described in the AIDA network. We also provided a clinical profile of patients with parenchymal lung involvement considering its prognostic relevance. Although providing a clinical landscape of these patients, further studies are needed to fully clarify this issue.

Id prodotto:

145541

Handle IRIS:

11562/1161354

ultima modifica:

8 maggio 2025

Citazione bibliografica:

Ruscitti, Piero; Vitale, Antonio; Di Cola, Ilenia; Caggiano, Valeria; Palumbo, Pierpaolo; Di Cesare, Ernesto; Hinojosa-Azaola, Andrea; Torres-Ruiz, Jiram; Guaracha-Basañez, Guillermo Arturo; Martín-Nares, Eduardo; Lopalco, Giuseppe; Morrone, Maria; Iannone, Florenzo; Giardini, Henrique A Mayrink; Cordeiro, Rafael Alves; de Brito Antonelli, Isabele Parente; Berardicurti, Onorina; Navarini, Luca; Ciccia, Francesco; Visconti, Maria Chiara; Iacono, Daniela; Direskeneli, Haner; Erten, Sukran; Yao, Haihong; Thabet, Maissa; Tharwat, Samar; Ragab, Gaafar; Gómez-Caverzaschi, Verónica; Sfikakis, Petros P; Fotis, Lampros; La Torre, Francesco; Maier, Armin; Karamanakos, Anastasios; Almaghlouth, Ibrahim A; Frassi, Micol; Tufan, Abdurrahman; Govoni, Marcello; Sota, Jurgen; Simonini, Gabriele; Emmi, Giacomo; Li Gobbi, Francesca; Parronchi, Paola; Costi, Stefania; Sarzi-Puttini, Piercarlo; Opris-Belinski, Daniela; Sfriso, Paolo; Tarsia, Maria; Maggio, Maria Cristina; Monti, Sara; Gündüz, Özgül Soysal; Rigante, Donato; Bartoloni, Elena; Verrecchia, Elena; Iagnocco, Annamaria; Viapiana, Ombretta; Bargagli, Elena; Batu, Ezgi D; Sebastiani, Gian Domenico; Del Giudice, Emanuela; Conti, Giovanni; Breda, Luciana; Gidaro, Antonio; Gicchino, Maria Francesca; Gaggiano, Carla; Brucato, Antonio Luca; Triggianese, Paola; Makowska, Joanna; Carubbi, Francesco; Farina, Nicola; Guggino, Giuliana; De Paulis, Amato; Mazzei, Maria Antonietta; Di Meglio, Nunzia; Lo Gullo, Alberto; Conforti, Alessandro; Ogunjimi, Benson; Calabrese, Laura; Rubegni, Pietro; Giardina, Annarita; Wiesik-Szewczyk, Ewa; Balistreri, Alberto; Fabiani, Claudia; Frediani, Bruno; Dagna, Lorenzo; Giacomelli, Roberto; Cantarini, Luca, The clinical assessment of lung involvement in patients with Still's disease, results from the multicentre international AIDA Network Still's Disease Registry «Rheumatology» , 2025 , pp. 1-5

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