Pubblicazioni

Autori:

Favalli, Ennio Giulio; Grossi, Francesco; Batticciotto, Alberto; Filippini, Matteo; Parisi, Simone; Viapiana, Ombretta; Gisondi, Paolo; Dapavo, Paolo; Dagna, Lorenzo; De Braud, Filippo

Titolo:

Spondyloarthritis and Risk of Malignancy: A Narrative Review on a Still Controversial Issue

Anno:

2025

Tipologia prodotto:

Articolo in Rivista

Tipologia ANVUR:

Articolo su rivista

Lingua:

Inglese

Referee:

No

Nome rivista:

RHEUMATOLOGY AND THERAPY

ISSN Rivista:

2198-6576

N° Volume:

12

Numero o Fascicolo:

1

Intervallo pagine:

25-36

Parole chiave:

Anti-rheumatic drugs; Cancer risk; Malignancy; Screening; Spondyloarthritis

Breve descrizione dei contenuti:

Current literature regarding cancer risk in rheumatic and musculoskeletal diseases (RMDs) is particularly poor and controversial, even though the incidence of malignancy in some patients with RMDs is considered to be increased compared with the general population. Malignancy may be a major comorbidity in subjects with spondyloarthritis (SpA) as the result of multifactorial mechanisms, from disease pathogenesis to the iatrogenic effect of immunomodulating drugs. Several recommendations for screening and management of cancer risk have been developed in recent years with the aim of improving the different outcomes in these patients. The goal of this narrative review is to provide an overview of the currently available evidence on the risk of malignancy connected with RMDs and examine the association of SpA with cancer and the potential impact of its treatment with biologic and targeted synthetic disease-modifying anti-rheumatic drugs on development of malignancy.

Id prodotto:

145540

Handle IRIS:

11562/1161355

ultima modifica:

8 maggio 2025

Citazione bibliografica:

Favalli, Ennio Giulio; Grossi, Francesco; Batticciotto, Alberto; Filippini, Matteo; Parisi, Simone; Viapiana, Ombretta; Gisondi, Paolo; Dapavo, Paolo; Dagna, Lorenzo; De Braud, Filippo, Spondyloarthritis and Risk of Malignancy: A Narrative Review on a Still Controversial Issue «RHEUMATOLOGY AND THERAPY» , vol. 12 , n. 1 , 2025 , pp. 25-36

Consulta la scheda completa presente nel repository istituzionale della Ricerca di Ateneo