Pubblicazioni

STEAP mRNA detection in serum of patients with solid tumours.  (2009)

Autori:
Valenti MT; Dalle Carbonare L; Donatelli L; Bertoldo F; Giovanazzi B; Caliari F; Lo Cascio V.
Titolo:
STEAP mRNA detection in serum of patients with solid tumours.
Anno:
2009
Tipologia prodotto:
Articolo in Rivista
Tipologia ANVUR:
Articolo su rivista
Lingua:
Inglese
Referee:
Nome rivista:
Cancer Letters
ISSN Rivista:
0304-3835
N° Volume:
273
Numero o Fascicolo:
1
Intervallo pagine:
122-126
Parole chiave:
STEAP; cancer; serum
Breve descrizione dei contenuti:
STEAP was identified by the strategy of suppression subtractive hybridizations in Los Angeles prostate cancer xenografts. It is expressed in prostate and other cancers, and not in most normal tissue; it can be used as a marker to evaluate biological samples from individuals suspected of having a disease associated with STEAP dysregulation, such as cancers, and may provide prognostic information useful in defining appropriate therapeutic options. The aim of this study was to test the STEAP mRNA detection in the serum of patients with different malignant tumours by using Real-Time reverse transcription PCR. The results were compared with biological samples obtained by age-matched non-malignant donors. Our data demonstrated that STEAP mRNA is detectable in serum of patients with different solid tumours whereas it is not amplifiable in non-malignant donors. This marker revealed with the molecular method of quantitative PCR in serum, may be useful to discriminate normal and cancer patients.
Id prodotto:
55091
Handle IRIS:
11562/323868
depositato il:
14 luglio 2012
ultima modifica:
16 agosto 2021
Allegati:
1
Citazione bibliografica:
Valenti MT; Dalle Carbonare L; Donatelli L; Bertoldo F; Giovanazzi B; Caliari F; Lo Cascio V., STEAP mRNA detection in serum of patients with solid tumours. «Cancer Letters» , vol. 273 , n. 12009pp. 122-126

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Progetti Collegati
Titolo Dipartimento Responsabili
Valutazione dell'RNA circolante in pazienti oncologici Dipartimento Medicina Maria Teresa Valenti
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